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        217-228 of 671 results for 'early childhood education'

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        Azithromycin reduces bronchial wall thickening in infants with cystic fibrosis

        COMBAT-CF showed that children aged 0-3 years treated with azithromycin did clinically better than placebo but there was no effect on CT-scores. We reanalysed CTs using an automatic bronchus-artery (BA) analysis. ...

        Research

        Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis

        Mucus hyperconcentration in cystic fibrosis (CF) lung disease is marked by increases in both mucin and DNA concentration. Additionally, it has been shown that half of the mucins present in bronchial alveolar lavage fluid from preschool-aged CF patients are present in as non-swellable mucus flakes. ...

        Research

        Systems biology and bile acid signalling in microbiome-host interactions in the cystic fibrosis lung

        The study of the respiratory microbiota has revealed that the lungs of healthy and diseased individuals harbour distinct microbial communities. Imbalances in these communities can contribute to the pathogenesis of lung disease. How these imbalances occur and establish is largely unknown. This review is focused on the genetically inherited condition of Cystic Fibrosis. ...

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        Investigating the Implications of CFTR Exon Skipping Using a Cftr Exon 9 Deleted Mouse Model

        Severity and disease progression in people with Cystic Fibrosis is typically dependent on their genotype. One potential therapeutic strategy for people with specific mutations is exon skipping with antisense oligonucleotides. CFTR exon 9 is an in-frame exon and hence the exclusion of this exon would excise only 31 amino acids but not alter the reading frame of the remaining mRNA. ...

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        Pseudomonas aeruginosa Resistance to Bacteriophages and Its Prevention by Strategic Therapeutic Cocktail Formulation

        Antimicrobial resistance poses a significant threat to modern healthcare as it limits treatment options for bacterial infections, particularly impacting those with chronic conditions such as cystic fibrosis (CF). Viscous mucus accumulation in the lungs of individuals genetically predisposed to CF leads to recurrent bacterial infections, necessitating prolonged antimicrobial chemotherapy. Pseudomonas aeruginosa infections are the predominant driver of CF lung disease, and airway isolates are frequently resistant to multiple antimicrobials. ...

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        Selective attention to threat, anxiety and glycaemic management in adolescents with type 1 diabetes

        Previous research has established that adolescents with type 1 diabetes (T1D) experience more anxiety symptoms than their healthy peers and are also more likely to develop an anxiety disorder. Research in cognitive psychology has found that selective attention favouring the processing of threatening information causally contributes to elevated levels of anxiety; however, this process has not been investigated in the context of T1D. ...

        Research

        “Beacon” Cyber App Project with Bankwest

        Helen Samantha Monks Veurink H SV MPH BA(Psych) PhD BSc PostGradDip MPH Senior Project Officer Research Officer 08 6319 1470 08 6319 1492 helen.monks@telethonkids.org.au Samantha.Veurink@telethonkids.org.au Senior Research Officer Research Officer ...

        Research

        School Attendance

        Each day of school missed makes a difference, with the effect on learning accumulating over time. From an early age, if children are taught that they need to 'show up' for school and make a commitment, this positive mentality aids academic and career success and brings benefits in adulthood. ...

        Research

        Gestational age and child development at school entry

        Studies have reported a dose-dependent relationship between gestational age and poorer school readiness. The study objective was to quantify the risk of developmental vulnerability for children at school entry, associated with gestational age at birth and to understand the impact of sociodemographic and other modifiable risk factors on these relationships. Linkage of population-level birth registration, hospital, and perinatal datasets to the Australian Early Development Census (AEDC), enabled follow-up of a cohort of 64,810 singleton children, from birth to school entry in either 2009, 2012, or 2015. ...

        Research

        Lowering Australia's defence against infectious diseases

        Australia's defence, infectious diseases ...

        Research

        The Future Healthy Countdown 2030: holding Australia to account for the health and wellbeing of future generations

        Fiona Stanley FJ FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) Patron 08 6319 1176 contact@telethonkids.org.au Patron Named Australian of the Year in 2003, Professor Fiona Stanley is a ...

        Research

        Electronic Use in Little Ones (EUiLO)

        Mary Brushe MB BPsych(Hons), PhD (Public Health) Senior Research Officer 08 6375 6102 mary.brushe@telethonkids.org.au Senior Research Officer @marybrushe she/her/hers Dr Brushe is a Senior Research Officer at Telethon Kids Institute whose research ...

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