Multidrug-resistant tuberculosis (MDR-TB) is a major global public health concern. However, there is a dearth of literature on whether MDR-TB and its medications impact maternal and perinatal outcomes, and when such evidence exists the findings are conflicting. This systematic review and meta-analysis aimed to examine the impact of MDR-TB and its medications during pregnancy on maternal and perinatal outcomes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

The re-emergence of scarlet fever poses a new global public health threat. The capacity of North-East Asian serotype M12 (emm12) Streptococcus pyogenes (group A Streptococcus, GAS) to cause scarlet fever has been linked epidemiologically to the presence of novel prophages ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Receiving vaccines at or close to their due date (vaccination timeliness) is a now key measure of program performance. However, studies comprehensively examining predictors of delayed infant vaccination are lacking. We aimed to identify predictors of short and longer-term delays in diphtheria-tetanus-pertussis (DTP) vaccination by dose number and ethnicity. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

This is a protocol for a Cochrane Review (intervention). The objectives were to assess the efficacy and safety of whole‐cell pertussis (wP) vaccinations in comparison to acellular pertussis (aP) vaccinations in early infancy for the prevention of atopic diseases in children. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

This study aimed to quantify the spatial and temporal patterns of dengue and their relationship to environmental factors in dengue-affected areas ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

Acute respiratory or febrile illness hospitalization during pregnancy was associated with increased risk of preterm birth and low birthweight birth ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

Respiratory syncytial virus (RSV) is a global cause of severe respiratory morbidity and mortality in infants. While preventive and therapeutic interventions are being developed, including antivirals, vaccines and monoclonal antibodies, little is known about the global molecular epidemiology of RSV. INFORM is a prospective, multicenter, global clinical study performed by ReSViNET to investigate the worldwide molecular diversity of RSV isolates collected from children less than 5 years of age. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Epidemic viral infections predominated as causes of childhood encephalitis in Australia. The leading causes include vaccine-preventable diseases ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Assess the safety and impact of the introduction of a guideline recommending early discharge of infants with fever without source at low risk of serious bacterial infection ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

We found that BCG, in a mouse model of neonatal polymicrobial sepsis, induced granulocyte colony-stimulating factor (G-CSF) within hours of administration ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

The findings of this postmarketing assessment of the safety of 2 new enhanced influenza vaccines support confidence in ongoing vaccine use ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Active vaccine safety surveillance leading to rapid detection of a safety signal would likely have resulted in earlier suspension of Fluvax from the vaccination programme ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020