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        Genome-wide association study of IgG1 responses to the choline-binding protein PspC of Streptococcus pneumoniae

        Delayed development of antibodies to S. pneumoniae in infancy is associated with the development of atopy and asthma. ...

        Research

        The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development

        Lung inflammation resulting from ARIs during infancy is linked to asthma development. ...

        Research

        Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect.

        Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity ...

        Research

        Prediction of peri-operative adverse respiratory events in children: The role of exhaled nitric oxide.

        Increased levels of exhaled nitric oxide (eNO) may be a more objective predictor in identifying children at higher risk of peri-operative adverse respiratory... ...

        Research

        Birth cohorts in asthma and allergic diseases: Report of a NIAID/NHLBI/MeDALL joint workshop

        Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases. ...

        Research

        Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of risk

        A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial... ...

        Research

        Identification of Der p 23, a peritrophin-like protein, as a new major dermatophagoides pteronyssinus allergen

        The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. ...

        Research

        T regulatory cells in childhood asthma

        Asthma is a chronic disease of the airways, most commonly driven by immuno-inflammatory responses to ubiquitous airborne antigens. ...

        Research

        Infant respiratory infections and later respiratory hospitalisation in childhood

        The aim of this study was to use total-population based data on an otherwise healthy population of children to assess the relationship between early... ...

        Research

        Lower anti-echovirus antibody responses in children presenting to hospital with asthma exacerbations.

        This article assesses the absolute and specific antibody titres to VP1 antigens of the gut-trophic enteroviruses, echovirus 30 and Sabin 1 poliovirus, in... ...

        Research

        Rationale, design and methods for the 22 year follow-up of the Western Australian Pregnancy Cohort (Raine) Study

        Young adulthood is a critical life period for health and health behaviours. ...

        Research

        The influence of sighing respirations on infant lung function measured using multiple breath washout gas mixing techniques

        There is substantial interest in studying lung function in infants, to better understand the early life origins of chronic lung diseases such as asthma. ...

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