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        Silver Russel syndrome in an aboriginal patient from Australia

        We report a 4-year-old Australian Aboriginal girl who was born at 32 weeks gestation with features strongly suggestive of Silver-Russell syndrome ...

        Research

        Dysregulated IL-1β-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine

        We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever ...

        Research

        Impact of biobanks on research outcomes in rare diseases: a systematic review

        This review made the important observation that registries with biobanks had the function of both stand-alone registries and stand-alone rare disease biobanks ...

        Research

        Prevalence of Racial Discrimination in a Cohort of Aboriginal and Torres Strait Islander Children

        This study looked at the frequency of racism experiences over time in a population of Aboriginal and Torres Strait Islander children ...

        Research

        Midwives’ attitudes, beliefs and concerns about childhood vaccination: A review of the global literature

        The majority of midwives supported vaccination, although a spectrum of beliefs and concerns emerged ...

        Research

        Active surveillance of 2017 seasonal influenza vaccine safety: An observational cohort study of individuals aged 6 months and older in Australia

        AusVaxSafety surveillance demonstrated comparable and expected safety outcomes for the 2017 quadrivalent inactivated influenza vaccine brands used in Australia ...

        Research

        ISPAD Clinical Practice Consensus Guidelines 2018: Assessment and management of hypoglycemia in children and adolescents with diabetes

        Hypoglycemia is the commonest acute complication of type 1 diabetes ...

        Research

        Renal and Cardiovascular Risk According to Tertiles of Urinary Albumin-to-Creatinine Ratio: The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT)

        Urinary albumin-to-creatinine ratios at the higher end of the normal range at the age of 10-16 years is associated with an increased risk of progression to microalbuminuria ...

        Research

        Reducing harms related to alcohol use in pregnancy – policy and practice recommendations

        This issues brief outlines opportunities for change to support reduction of harms related to alcohol use in pregnancy ...

        Research

        Exposure to chorioamnionitis alters the monocyte transcriptional response to the neonatal pathogen Staphylococcus epidermidis

        Our findings suggest that prenatal exposure to inflammation may alter the risk of sepsis in preterm infants partly by modulation of monocyte responses to pathogens ...

        Research

        PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

        Our findings present a novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis ...

        Research

        Early life innate immune signatures of persistent food allergy

        Early life innate immune dysfunction may represent a key immunological driver and predictor of persistent food allergy in childhood ...

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