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        Impact of biobanks on research outcomes in rare diseases: a systematic review

        This review made the important observation that registries with biobanks had the function of both stand-alone registries and stand-alone rare disease biobanks ...

        Research

        Renal and Cardiovascular Risk According to Tertiles of Urinary Albumin-to-Creatinine Ratio: The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT)

        Urinary albumin-to-creatinine ratios at the higher end of the normal range at the age of 10-16 years is associated with an increased risk of progression to microalbuminuria ...

        Research

        ISPAD Clinical Practice Consensus Guidelines 2018: Assessment and management of hypoglycemia in children and adolescents with diabetes

        Hypoglycemia is the commonest acute complication of type 1 diabetes ...

        Research

        Reducing harms related to alcohol use in pregnancy – policy and practice recommendations

        This issues brief outlines opportunities for change to support reduction of harms related to alcohol use in pregnancy ...

        Research

        Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy

        Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms. ...

        Research

        Maternal and family factors and child eating pathology: Risk and protective relationships

        This study aimed to identify maternal and family factors that may predict increases or decreases in child eating disorder symptoms over time, accounting for... ...

        Research

        Waning vaccine immunity in teenagers primed with whole cell and acellular pertussis vaccine: Recent epidemiology

        The recent epidemics of pertussis (whooping cough) in parts of the USA and Australia have led to the largest numbers of annual cases reported in over half a... ...

        Research

        Mother's love for bacterial babies: the commitment of Audrey Michael, Mition Yoannes and Tilda Orami to medical research

        Face-to-face interviews were conducted with all three women for the purpose of profiling women who are leaders in health and medicine in Papua New Guinea. ...

        Research

        Multinodular goiter in children: An important pointer to a germline DICER1 mutation

        This paper is a clinical report of a boy presenting with a kidney cyst. Family history and genetic analysis revealed the family had a mutation in the DICER1... ...

        Research

        Assessment and management of hypoglycemia in children and adolescents with diabetes

        This paper provides clinical practice guidelines for treating low blood sugar in children and adolescents with Type 1 diabetes. ...

        Research

        Environmental, personal, and genetic determinants of response to vitamin D supplementation in older adults

        We aimed to examine genetic and nongenetic determinants of change in serum 25-hydroxyvitamin D (25(OH)D) after supplementation. ...

        Research

        Human active X-specific DNA methylation events showing stability across time and tissues

        The phenomenon of X chromosome inactivation in female mammals is well characterised and remains the archetypal example of dosage compensation via monoallelic... ...

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