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        13-24 of 538 results for 'Gene'

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        Research

        Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis

        We assessed 30 sibships and 89 parent/case trios of presumed ocular toxoplasmosis (POT) to evaluate associations with polymorphisms in the NOD2 gene. ...

        Research

        Gene regulation by 1,25-dihydroxyvitamin D3 in CD4+CD25+ cells is enabled by IL-2

        Vitamin D may be responsible for reducing the development and severity of autoimmune and allergic diseases. Topically applied 1,25-dihydroxyvitamin D(3) (1,25(O ...

        Research

        Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukaemia

        Several studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukaemia (ALL). ...

        Research

        MACROD2 gene associated with autistic-like traits in a general population sample

        The MACROD2 gene is a strong positional candidate risk factor for autistic-like traits in the general population ...

        Research

        Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood

        The effect of breast-feeding on the development of allergic disease is uncertain ...

        Research

        No simple answers for the Finnish and Russian Karelia allergy contrast: Methylation of CD14 gene

        The methylation variation in the promoter region of CD14 gene did not explain the asthma and allergy contrast between Finnish and Russian Karelian children ...

        Research

        Target validation of the inosine monophosphate dehydrogenase (IMPDH) gene in Cryptosporidium using Phylomer® peptides

        Cryptosporidiosis, a gastroenteric disease characterised mainly by diarrheal illnesses in humans and mammals is caused by infection with the protozoan... ...

        Research

        Gene-vitamin D interactions on food sensitization: A prospective birth cohort study

        It has been hypothesized that vitamin D deficiency (VDD) contributes to the development of food sensitization (FS) and then food allergy. ...

        Research

        Effective adenovirus-mediated gene transfer into neural stem cells derived from human embryonic stem cells

        Human embryonic stem cell-derived neural stem cells (hESC-NSCs) are an attractive cell type for studying ...

        Research

        Severe congenital cutis laxa: Identification of novel homozygous LOX gene variants in two families

        We report three babies from two families with a severe lethal form of congenital cutis laxa. All three had redundant and doughy-textured skin and two siblings from one family had facial dysmorphism. Echocardiograms showed thickened and poorly contractile hearts, arterial dilatation and tortuosity. Post-mortem examination in two of the babies further revealed widespread ectasia and tortuosity of medium and large sized arteries, myocardial hypertrophy, rib and skull fractures. ...

        Research

        Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

        Pre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms. ...

        Research

        Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity

        Our result highlighted that miRNA-target gene network contributes to human disease genetics in a cell type-specific manner ...

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