This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of children and to identify extensive DNA stranding in the MEF from children with AOM ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• December 2012

Chris Peter Brennan-Jones Richmond C PC PhD MBBS MRCP(UK) FRACP Head, Ear Health Head, Vaccine Trials Group chris.brennan-jones@telethonkids.org.au Senior Research Fellow, Ear Health Head, Vaccine Trials Group Associate Professor Chris Brennan-Jones ...

• 1. Telethon Kids Institute
• Projects

Otitis media (OM; middle ear infection) is the most common reason for pre-school children to visit a doctor, be prescribed antimicrobials, or undergo surgery. Recent Cochrane reviews of clinical trials have identified that antibiotics and grommet surgery are only moderately effective in treating OM, with recurrent or persistent infection observed in one-third of children. Research efforts are focusing on developing improved therapies to treat OM and prevent disease recurrence. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

To assess the effects of aural toilet procedures for people with chronic suppurative otitis media ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

To assess the relative effectiveness of topical versus systemic antibiotics for people with chronic suppurative otitis media ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

In Australia the 7-valent pneumococcal conjugate vaccine (PCV7) is administered at 2, 4 and 6 months of age, with no booster dose. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• July 2011

Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

To assess the effects of adding a topical steroid to topical antibiotics in the treatment of people with chronic suppurative otitis media ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms of CSOM are ear discharge and hearing loss. Antibiotics are the most common treatment for CSOM, which act to kill or inhibit the growth of micro-organisms that may be responsible for the infection. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

Treatment of chronic suppurative otitis media with topical antibiotics probably results in an increase in resolution of ear discharge compared with boric acid ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

Deborah Chris Tamara Lehmann Brennan-Jones Veselinovic D C TV AO, MBBS, MSc PhD MClinAud Honorary Emeritus Fellow Head, Ear Health Clinical Research Officer/PhD student chris.brennan-jones@telethonkids.org.au tamara.veselinovic@telethonkids.org.au ...

• 1. Telethon Kids Institute
• Projects

We investigated predictors of nasopharyngeal carriage in Australian Aboriginal and non-Aboriginal children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• June 2011