The functionality and effects of TLR7 and TLR8 polymorphisms on cellular and antibody responses was investigated after the first measles vaccine dose. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

Ingrid Pat Laing Holt IL PG BSc PhD PhD, DSc, FRCPath, FRCPI, FAA Head, Children's Respiratory Science Emeritus Honorary Researcher 6319 1828 Ingrid.laing@telethonkids.org.au@hotmail.cmo Patrick.Holt@telethonkids.org.au Honorary Research Fellow ...

• 1. Telethon Kids Institute
• Projects

Ingrid Anthony Deborah Jonatan Thomas Laing Kicic Strickland Leffler Iosifidis IL A DH JL TI BSc PhD BSc (Hons) PhD PhD PhD BSc BMedSci(Hons) PhD Head, Children's Respiratory Science Rothwell Family Fellow; Head, Airway Epithelial Research Program ...

• 1. Telethon Kids Institute
• Projects

The epithelium is integral to the protection of many different biological systems and for the maintenance of biochemical homeostasis. Emerging evidence suggests that particular children have epithelial vulnerabilities leading to dysregulated barrier function and integrity, that resultantly contributes to disease pathogenesis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Anthony Belinda Ingrid Kicic Hales Laing A BJ IL BSc (Hons) PhD BSc (Hons) PhD BSc PhD Rothwell Family Fellow; Head, Airway Epithelial Research Senior Manager, Research Platforms Head, Children's Respiratory Science 6319 1828 Anthony.Kicic@ ...

• 1. Telethon Kids Institute
• Projects

Impaired interferon response and allergic sensitization may contribute to virus-induced wheeze and asthma development in young children. Plasmacytoid dendritic cells play a key role in antiviral immunity as critical producers of type I interferons.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Anthony David Stephen Susan Kicic Martino Stick Prescott A DM SM SL BSc (Hons) PhD BSc PhD MB BChir PhD MRCP FRACP MBBS BMedSci PhD FRACP Rothwell Family Fellow; Head, Airway Epithelial Research Head, Clinical Epigenetics Head, P4 Respiratory Health ...

• 1. Telethon Kids Institute
• Projects

André Graham Ingrid Schultz Hall Laing AS GL IL MBChB, PhD, FRACP BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc PhD Program Head, Respiratory Health RFA Honorary Research Associate Head, Children's Respiratory Science 6319 1828 Ingrid.laing@ ...

• 1. Telethon Kids Institute
• Projects
• Past projects

Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subsequent migration of immune cells into the airways remains incompletely understood. Cellular and molecular profiling of PBMC was employed on paired samples obtained from atopic asthmatic children during acute virus-associated exacerbations and later during convalescence. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Alexander Anthony Deborah Emma Jean-Francois Pat Larcombe Kicic Strickland de Jong Lauzon-Joset Holt A A DH EdJ JFLJ PG BScEnv (Hons) PhD BSc (Hons) PhD PhD PhD, DSc, FRCPath, FRCPI, FAA Team Leader, Respiratory Environmental Health Rothwell Family ...

• 1. Telethon Kids Institute
• Projects

André Graham Ingrid Schultz Hall Laing AS GL IL MBChB, PhD, FRACP BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc PhD Program Head, Respiratory Health RFA Honorary Research Associate Head, Children's Respiratory Science 6319 1828 Ingrid.laing@ ...

• 1. Telethon Kids Institute
• Projects

Anthony Christopher David Ingrid Shannon Thomas Kicic Blyth Martino Laing Simpson Iosifidis A CC DM IL SS TI BSc (Hons) PhD MBBS (Hons) DCH FRACP FRCPA PhD BSc PhD BSc PhD BMedSci (hons), PhD BSc BMedSci(Hons) PhD Rothwell Family Fellow; Head, ...

• 1. Telethon Kids Institute
• Projects