In utero exposure to arsenic via drinking water increases the risk of lower respiratory tract infections during infancy and mortality from bronchiectasis in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

This work initially examines particle deposition in a Weibull-type geometry, comparing traditional computational fluid dynamics approaches with a novel... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

Exposure to diesel exhaust particles (DEP) is thought to exacerbate many pre-existing respiratory diseases. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• September 2012

The aim of our investigation was to assess the chemical composition of a range of e-liquids available in Australia, focusing on nicotine and other potentially harmful compounds ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

Mucopolysaccharidosis type IIIA (MPS IIIA) is characterized by neurological and skeletal pathologies caused by reduced activity of the lysosomal hydrolase, sulfamidase, and the subsequent primary accumulation of undegraded heparan sulfate (HS). Respiratory pathology is considered secondary in MPS IIIA and the mechanisms are not well understood.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• June 2024

Electronic cigarettes (e-cigarettes) are often perceived to be safer than smoking, which has led to some women switching to e-cigarettes during pregnancy. However, the effects of switching from smoking to e-cigarettes on both pregnancy outcomes and the foetus are largely unknown. This study aimed to investigate the effects of switching from tobacco smoking to e-cigarette use in very early pregnancy on birth outcomes, neurodevelopment and behaviour of the offspring. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Despite their increasing popularity, and Australia's unique regulatory environment, how and why Australian adults use e-cigarettes and their perceptions of their safety, efficacy and regulation have not been extensively reported before. In this study, we screened 2217 adult Australians with the aim of assessing these questions in a sample of current or former e-cigarette users. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

Atmospheric carbon dioxide (CO2) levels are currently at 418 parts per million (ppm), and by 2100 may exceed 900 ppm. The biological effects of lifetime exposure to CO2 at these levels is unknown. Previously we have shown that mouse lung function is altered by long-term exposure to 890 ppm CO2. Here, we assess the broader systemic physiological responses to this exposure. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

It is therefore clear that gavage can have significant impacts on experimental animals in terms of their stress response and overall morbidity and mortality ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

All alterations to lung mechanics following in utero arsenic exposure were recovered by adulthood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

Electronic cigarettes (ECs) have been rapidly gaining ground on conventional cigarettes due to their efficiency in ceasing or reducing tobacco consumption,... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• March 2015

Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019