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        Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthma

        Evidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells. ...

        Research

        Defective respiratory tract immune surveillance in asthma : A primary causal factor in disease onset and progression

        The relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate. ...

        Research

        High expression of connective tissue growth factor accelerates dissemination of leukaemia

        Functional role of CTGF in altering disease progression in a lymphoid malignancy ...

        Research

        A bivalent Neisseria meningitidis recombinant lipidated factor H binding protein vaccine in young adults:

        Neisseria meningitidis is a leading cause of meningitis and septicaemia, but a broadly-protective vaccine against endemic serogroup B disease is not licensed... ...

        Research

        Deregulated expression of connective tissue growth factor is linked to poor outcome in human cancer

        Connective tissue growth factor (CTGF/CCN2) has long been associated with human cancers. The role it plays in these neoplasms is diverse and tumour specific. ...

        Research

        Dysregulation of innate immunity in ulcerative colitis patients who fail anti-tumor necrosis factor therapy

        Study the innate immune function in ulcerative colitis patients who fail to respond to anti-tumor necrosis factor therapy ...

        Research

        The factor structure of the eating disorder examination in clinical and community samples

        We investigated whether children who are heavier at birth have an increased risk of type 1 diabetes ...

        Research

        Confirmatory factor analysis of the Eating Disorder Examination-Questionnaire (EDE-Q)

        To compare the goodness-of-fit of five models of Eating Disorder Examination-Questionnaire (EDE-Q) data, in clinical and community samples. ...

        Research

        DeepCAGE Transcriptomics Reveal an Important Role of the Transcription Factor MAFB in the Lymphatic Endothelium

        VEGFR-3 signaling plays a central role in lymphatic biology, both in the development of the lymphatic network during embryogenesis as well as in... ...

        Research

        Alexithymia as a risk factor for poor emotional outcomes in adults with acquired brain injury

        Emotional disorders are pervasive in the acquired brain injury (ABI) population, adversely affecting quality of life and rehabilitation. This study aimed to explore the unique associative effects of alexithymia as measured by the Perth Alexithymia Questionnaire. ...

        Research

        The pet factor - Companion animals as a conduit for getting to know people, friendship formation and social support

        Pet owners were significantly more likely to get to know people in their neighborhood than non-pet owners. ...

        Research

        Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?

        We conducted an investigation of all cases coded as anaphylaxis presenting to the main tertiary PED in Perth, Australia, where all coding is performed by staff. ...

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