The prevalence of IgE binding to the group 15 and 18 house dust mite (HDM) allergens of the Dermatophagoides species... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• October 2012

Intrauterine growth restriction (IUGR) is associated with asthma. Murine models of IUGR have altered airway responsiveness in the absence of any inflammatory exposure. Given that a primary feature of asthma is airway inflammation, IUGR-affected individuals may develop more substantial respiratory impairment if subsequently exposed to an allergen. This study used a maternal hypoxia-induced mouse model of IUGR to determine the combined effects of IUGR and allergy on airway responsiveness. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

The dramatic rise in allergic disease has occurred in tandem with recent environmental changes and increasing indoor lifestyle culture. While multifactorial, one consistent allergy risk factor has been reduced sunlight exposure. However, vitamin D supplementation studies have been disappointing in preventing allergy, raising possible independent effects of ultraviolet (UV) light exposure. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

To determine whether changes in 24-hour average background ozone (O₃), nitrogen dioxide (NO₂), carbon monoxide (CO) and particulates < 10 μm (PM₁₀) increase the ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

Severe winter lower respiratory infections in early life are known to be major risk factors for subsequent development of asthma, and it is also known that the high susceptibility to these infections in infants is due to the functional immaturity of ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Human Immunology

Pat Belinda Holt Hales PG BJ PhD, DSc, FRCPath, FRCPI, FAA BSc (Hons) PhD Emeritus Honorary Researcher Senior Manager, Research Platforms Patrick.Holt@telethonkids.org.au belinda.hales@telethonkids.org.au Emeritus Honorary Researcher Senior Manager ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Human Immunology