The prevalence of multiple sclerosis follows a latitude gradient, with increased disease at higher latitudes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

This study aimed to identify a CIS peripheral blood signature that may provide clues for potential immunomodulatory approaches early in disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• June 2017

Diabetes mellitus is one of the most common chronic metabolic disorders worldwide, and its incidence in Asian countries is alarmingly high. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

Alexander David Martyn Larcombe Martino Symons A DM MS BScEnv (Hons) PhD BSc PhD B.A. (Hons) PhD. Team Leader, Respiratory Environmental Health Head, Clinical Epigenetics Honorary Research Associate 08 6319 1672 David.Martino@telethonkids.org.au ...

• 1. Telethon Kids Institute
• Projects

Rett syndrome (RTT) is an X linked neuro-developmental disorder affecting mostly girls. Mutations in the coding region of MECP2 are found in 80% of classic... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2006
• June 2006

Sébastien Laurence Rishi Sury Malinge Cheung Kotecha SM LC RS PhD BPharm (Hons) MBA PhD MB ChB (Hons) MRCPCH FRACP PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior Research ...

• 1. Telethon Kids Institute
• Projects

Larissa Alix Penelope Marion Woolard Strauss LM AW PS BPsych(Hons) BPsych (Hons), PhD BA, MPH, PhD Research Assistant & PhD Student Senior Research Fellow Research Fellow in Youth Suicide Prevention 08 6319 1823 08 6319 1297 larissa.marion@ ...

• 1. Telethon Kids Institute
• Projects

Prenatal alcohol exposure is associated with a range of adverse offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA methylation in offspring cells and tissues, providing evidence for a potential mechanistic link to Fetal Alcohol Spectrum Disorder. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Children with Down syndrome (constitutive trisomy 21) that develop acute lymphoblastic leukemia (DS-ALL) have a 3-fold increased likelihood of treatment-related mortality coupled with a higher cumulative incidence of relapse, compared with other children with B-cell acute lymphoblastic leukemia (B-ALL). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

The global disruption of the COVID-19 pandemic has impacted the life of every child either directly or indirectly. This review explores the pathophysiology, immune response, clinical presentation and treatment of COVID-19 in children, summarising the most up-to-date data including recent developments regarding variants of concern. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

We still do not have a RF vaccine, although the recent announcement that the Australian and New Zealand governments are jointly sponsoring a program to fast... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• September 2013

Despite initial improvements in survival of infants with ALL since establishment of the first pediatric cooperative group ALL trials, the poor outcome has... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014