It is therefore clear that gavage can have significant impacts on experimental animals in terms of their stress response and overall morbidity and mortality ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

We aim to determine whether multidrug-resistant tuberculosis and its medications during pregnancy impact maternal and perinatal outcomes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

Structural and numerical alterations of chromosome 21 are extremely common in hematological malignancies. While the functional impact of chimeric transcripts from fused chromosome 21 genes such as TEL-AML1, AML1-ETO, or FUS-ERG have been extensively studied, the role of gain of chromosome 21 remains largely unknown. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

At the end of a 60-day course of narrowband UVB phototherapy, administered to individuals with early multiple sclerosis, there were changes in the relative proportions of circulating B-cell subsets. This study investigated phototherapy-associated changes to cytokine responses of B cells when exposed to a TLR7 ligand. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

School-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

This study aimed to (1) examine the strength of the association between mental disorders/mental health problems, risk behaviours and tobacco smoking among Australian adolescents, (2) compare rates of tobacco smoking among Australian adolescents with major depressive disorder, attention-deficit/hyperactivity disorder and/or conduct disorder in 2013/14 vs 1998, and (3) identify the extent to which an association between tobacco smoking and mental health problems among adolescents can be attributed to non-mental health risk factors. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

IL7 and glucocorticoids coordinately drive aberrant activation of PIM1 and suggests that T-ALL and T-LBL patients could benefit from PIM inhibition ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

We must celebrate success and hope through a process of mapping and building recovery capital in the justice context at an individual and institutional level ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Our work has identified a clinically relevant host-derived factor that may participate in shaping early events in the aetiology of CF respiratory disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Mild traumatic brain injury (mTBI) is a complex injury with heterogeneous physical, cognitive, emotional and functional outcomes. Many who sustain mTBI recover within 2 weeks of injury; however, approximately 10%-20% of individuals experience mTBI symptoms beyond this 'typical' recovery timeframe, known as persistent post-concussion symptoms (PPCS). Despite increasing interest in PPCS, uncertainty remains regarding its prevalence in community-based populations and the extent to which poor recovery may be identified using early predictive markers. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

These findings suggest that genetic variants at the VDR locus may play a role in acute wheeze/asthma severity in children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Hot spots and clusters of both species were isolated in the central southern part of Bhutan bordering India ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020