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        A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

        To introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation. ...

        Research

        Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and Abscess

        We conducted a systematic review of clinical trials and observational studies that address the utility of SXT for SSTI treatment, caused by either GAS or MRSA ...

        Research

        Risk of Mortality into Adulthood According to Gestational Age at Birth

        To quantify the independent risks of neonatal, postneonatal, 1 to 5 and 6 to 30 year mortality by gestational age and investigate changes in survival over time. ...

        Research

        Prospective cohort study of childhood behaviour problems and adolescent sexual risk-taking: Gender matters

        This study sought to determine relationships, by gender, between childhood behaviour problems and adolescent risky sexual behaviours and substance use. ...

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        The potential of phage therapy in cystic fibrosis

        This review summarises the phage-microbe-human lung interactions in CF that must be addressed to successfully develop and deliver phage to CF airways ...

        Research

        Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology

        Lack of agreement about criteria and terminology for children's language problems affects access to services as well as hindering research and practice. ...

        Research

        A prospective audit of pain profiles following general and urological surgery in children

        To determine the duration and severity of acute postoperative pain experienced by children undergoing 8 different general and urological procedures. ...

        Research

        Measurement of Sedentary Behaviors or "downtime" in Rett Syndrome

        This study aimed to validate measures of sedentary time in individuals with Rett syndrome. ...

        Research

        Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the pregnancy and childhood epigenetics (PACE) consortium

        we meta-analysed the association between pre-pregnancy maternal BMI and methylation at over 450,000 sites in newborn blood DNA, across 19 cohorts. ...

        Research

        Australian guide to the diagnosis of foetal alcohol spectrum disorder: A summary

        The Australian Guide to the Diagnosis of Fetal Alcohol Spectrum Disorder has been developed, funded by the Commonwealth Department of Health ...

        Research

        The continuity and duration of depression and its relationship to non-suicidal self-harm and suicidal ideation and behavior in adolescents 12–17

        Overlap between non-suicidal self-harm and suicidal ideation and behavior in young people with both symptom continuity and symptom duration implicated in this association ...

        Research

        Increased heterogeneity of airway calibre in adult rats after hypoxia-induced intrauterine growth restriction

        The rat model demonstrates that intrauterine growth restriction leads to a more heterogeneous distribution of airway lumen calibre in adulthood ...

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