Among genes present in all group A streptococci (GAS), those encoding M-fibril and T-pilus proteins display the highest levels of sequence diversity, giving rise to the two primary serological typing schemes historically used to define strain. A new genotyping scheme for the pilin adhesin and backbone genes is developed and, when combined with emm typing, provides an account of the global GAS strain population. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• May 2024

The transition to parenthood is a high-risk period for many parents and is an important period for child development. Research has identified that parental mental health, reflective functioning (capacity to consider mental states of oneself and others) and coparenting (capacity to work together well as a parenting team) may be particularly significant predictors of later child outcomes, however these factors have seldom been considered together. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Alpha-1 adrenoceptors are overexpressed in the epidermis of a subgroup of patients with complex regional pain syndrome. Activating α 1 -adrenoceptors in epidermal cells increases production of the proinflammatory cytokine interleukin-6, a mediator of inflammation. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

There is scant literature about the management of stillbirth and the subsequent risk of severe maternal morbidity (SMM). We aimed to assess the risk of SMM associated with stillbirths compared with live births and whether this differed by the presence of maternal comorbidities. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Globally, life expectancy from birth increased from 61·7 years in 1980 to 71·8 years in 2015 ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• October 2016

The present study analyzed the concurrent and longitudinal relations among cognitive flexibility, theory of mind, and hyperactivity/inattention. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• January 2014

It is therefore clear that gavage can have significant impacts on experimental animals in terms of their stress response and overall morbidity and mortality ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

To assess the scale of ethnic inequalities in severe maternal morbidity (SMM) rates and quantify the contribution of maternal characteristics to these disparities. This is a retrospective cohort study. A whole-of-population linked administrative data from 2002 to 2015 in Western Australia. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

The Child Behavior Checklist (CBCL) is a commonly used measure of child and adolescent functioning, which includes seven items that can be aggregated to provide a purportedly valid measure of sleep functioning. The objective of this study was to examine the convergent validity of the CBCL in a paediatric ADHD population and to evaluate the sensitivity of the instrument when benchmarked against the Sleep Disorders Scale for Children (SDSC). ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Electronic cigarettes (ECs) have been rapidly gaining ground on conventional cigarettes due to their efficiency in ceasing or reducing tobacco consumption,... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• March 2015

The current study investigated whether being exposed to maladaptive parenting (high hostility and low warmth) and/or marital conflict in infancy is... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

Genome sequencing and phylogenetic analysis of a quorum sensing positive Psychrobacter isolate identified several quorum sensing associated systems ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019