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        253-264 of 1073 results for 'curtin'

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        The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution

        The bone marrow microenvironment (BMM) plays a key role in leukemia progression, but its molecular complexity in pre-B cell acute lymphoblastic leukemia (B-ALL), the most common cancer in children, remains poorly understood. To gain further insight, we used single-cell RNA sequencing to characterize the kinetics of the murine BMM during B-ALL progression. ...

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        Rheumatic heart disease in pregnancy: Profile of women admitted to a Western Australian tertiary obstetric hospital

        This retrospective study assessed maternal and perinatal outcomes for women with rheumatic heart disease admitted to the largest tertiary obstetric hospital ...

        Research

        Sensitivity of the child behaviour checklist sleep items and convergent validity with the Sleep Disorders Scale for Children in a paediatric ADHD

        The Child Behavior Checklist (CBCL) is a commonly used measure of child and adolescent functioning, which includes seven items that can be aggregated to provide a purportedly valid measure of sleep functioning. The objective of this study was to examine the convergent validity of the CBCL in a paediatric ADHD population and to evaluate the sensitivity of the instrument when benchmarked against the Sleep Disorders Scale for Children (SDSC). ...

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        Can the CHA2 DS2 -VA schema be used to decide on anticoagulant therapy in Aboriginal and other Australians with non-valvular atrial fibrillation?

        The Australasian guidelines recommend use of the CHA2 DS2 -VA schema to stratify ischaemic stroke risk in patients with non-valvular atrial fibrillation (N-VAF) and determine risk thresholds for recommending oral anticoagulant (OAC) therapy. However, the CHA2 DS2 -VA score has not been validated in a representative Australian population cohort with N-VAF, including in Aboriginal people who are known to have a higher age-adjusted stroke risk than other Australians. ...

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        Topical antibiotics for chronic suppurative otitis media

        To assess the effects of topical antibiotics for people with chronic suppurative otitis media. ...

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        Reflections on How Tinnitus Impacts the Lives of Children and Adolescents

        The aim of this study was to generate a conceptual framework describing which aspects of children and adolescents' lives are affected by chronic tinnitus. ...

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        Achieving universal electrification of rural healthcare facilities in sub-Saharan Africa with decentralized renewable energy technologies

        A potential response to the COVID-19 pandemic in sub-Saharan Africa (SSA) with long-term benefits is to provide electricity for medical equipment in rural health centers and communities. This study identifies a large gap in the electrification of healthcare facilities in SSA, and it shows that decentralized photovoltaic systems can offer a clean, reliable, quick, and cost-effective solution. ...

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        Implementation of the National Guideline for the Assessment and Diagnosis of ASD in Australia – Health Sector Capacity Building

        Andrew Whitehouse Watch and listen to Andrew AJ PhD Angela Wright Bennett Professor of Autism Research at Telethon Kids Institute; Director, CliniKids Andrew.Whitehouse@telethonkids.org.au Angela Wright Bennett Professor of Autism Research at ...

        Research

        The NZ BPG Pharmacokinetics Study

        Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au Institute Director; Head, Strep A Translation; Co-Founder of REACH Professor ...

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        Global estimates of the number of pregnancies at risk of malaria from 2007 to 2020: a demographic study

        The most recent global estimates of the number of pregnancies at risk of Plasmodium falciparum and Plasmodium vivax malaria infection are from 2007. To inform global malaria prevention and control efforts, we aimed to estimate the global distribution of pregnancies at risk of malaria infection from 2007 to 2020. ...

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        Malaria eradication within a generation: ambitious, achievable, and necessary

        Momentum towards eradication has been building for decades, and more than half of the world's countries are now malaria free ...

        Research

        Spatiotemporal patterns of tuberculosis in Hunan province, China

        Tuberculosis (TB) is the leading cause of death from a bacterial pathogen worldwide. China has the third highest TB burden in the world, with a high reported burden in Hunan Province (amongst others). This study aimed to investigate the spatial distribution of TB and identify socioeconomic, demographic, and environmental drivers in Hunan Province, China. Numbers of reported cases of TB were obtained from the Tuberculosis Control Institute of Hunan Province, China. ...

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