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        Immune-mediated ECM depletion improves tumour perfusion and payload delivery

        We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds ...

        Research

        Child and adolescent psychiatry training in Australia and New Zealand

        This article highlights the requirements of the training programs for Child and Adolescent Psychiatry in Australia and New Zealand ...

        Research

        Tumor necrosis factor α induces α1B-adrenergic receptor expression in keratinocytes

        Our results suggest that inflammatory cytokines released during injury stimulate α1-AR expression in keratinocytes ...

        Research

        The incidence of sore throat and group A streptococcal pharyngitis in children at high risk of developing acute rheumatic fever: A systematic review and meta-analysis

        Group A streptococcal (GAS) pharyngitis has traditionally been considered the sole precursor of acute rheumatic fever (ARF). Evidence from Australia, however, suggests that GAS skin infections may contribute to the pathogenesis of ARF. ...

        Research

        Feasibility of a Consumer Centred Tobacco Management intervention in Community Mental Health Services in Australia

        This study tested a new program for helping smokers with severe mental illness to reduce their tobacco use, together with determining the feasibility of such research in community mental health settings in Australia. ...

        Research

        Pregnancy and birth outcomes of mothers with intellectual disability and their infants: Advocacy needed to improve well-being

        For mothers with intellectual disability, modifiable risk factors for adverse outcomes need addressing ...

        Research

        MK2 inhibition induces p53-dependent senescence in glioblastoma cells

        In response to DNA damaging chemotherapy, targeting MK2 in p53-mutated cells produces a phenotype that is distinct from the p53-deficient phenotype ...

        Research

        Raising strong, solid Koolunga: Values and beliefs about early child development among Perth's Aboriginal community

        We detail the unique findings from an Aboriginal early child development research project with a specific focus on the Nyoongar/Aboriginal community of Perth ...

        Research

        Psychosocial disadvantage and residential remoteness is associated with Aboriginal women's mental health prior to childbirth

        Optimal mental health in the pre-conception, pregnancy and postpartum periods is important for both maternal and infant wellbeing. Few studies, however, have focused on Indigenous women and the specific risk and protective factors that may prompt vulnerability to perinatal mental disorders in this culturally diverse population. ...

        Research

        Facilitators and barriers to the implementation of motivational interviewing for bullying perpetration in school settings

        Results indicated a number factors which influenced the uptake of Motivational Interviewing in schools ...

        Research

        Microbiome and Functional Analysis of a Traditional Food Process: Isolation of a Novel Species (Vibrio hibernica) With Industrial Potential

        Vibrio hibernica is capable of metabolizing a unique carbohydrate profile at low temperatures ...

        Research

        Factors associated with pneumococcal carriage in children and adults in Fiji, using four cross-sectional surveys

        This study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji. We used data from four annual cross-sectional surveys, pre- and post-introduction of ten-valent pneumococcal conjugate vaccine in October 2012. Infants, toddlers, children, and their caregivers participated. Pneumococci were detected and quantified using lytA qPCR, with molecular serotyping by microarray. Logistic and quantile regression were used to determine predictors of pneumococcal carriage and density, respectively. ...

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