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        Protocol for spatial prediction of soil transmitted helminth prevalence in the Western Pacific region using a meta-analytical approach

        Soil transmitted helminth infections are estimated to impact 24% of the world's population and are responsible for chronic and debilitating morbidity. Disadvantaged communities are among the worst affected and are further marginalized as infection prevalence fuels the poverty cycle. ...

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        The role of exome sequencing in childhood interstitial or diffuse lung disease

        Children’s interstitial and diffuse lung disease (chILD) is a complex heterogeneous group of lung disorders. Gene panel approaches have a reported diagnostic yield of ~ 12%. No data currently exist using trio exome sequencing as the standard diagnostic modality. ...

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        ‘Stranger danger’, ‘abduction risks’ and ‘fear’: Media coverage of children's independent mobility and parental attitudes

        The media plays a powerful role in shaping health-related attitudes and behaviours. We investigated media reports about children's independent mobility (CIM) and associations with parental attitudes towards CIM. CIM-related media reports (newspaper, online, television) during a 3-month period were extracted from two databases. ...

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        Through the kids ... we connected with our community: Children as catalysts of social capital

        Both children and adults benefit from living in communities and neighborhoods that are rich in social capital. ...

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        Early vocabulary development: The importance of joint attention and parent-child book reading

        The current study brought a bioecological approach to children’s early vocabulary development using data from the Longitudinal Study of Australian Children... ...

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        RAD51-Mediated DNA Homologous Recombination Is Independent of PTEN Mutational Status

        PTEN mutation occurs in a variety of aggressive cancers and is associated with poor patient outcomes. Recent studies have linked mutational loss of PTEN to reduced RAD51 expression and function, a key factor involved in the homologous recombination (HR) pathway. However, these studies remain controversial, as they fail to establish a definitive causal link to RAD51 expression that is PTEN-dependent, while other studies have not been able to recapitulate the relationship between the PTEN expression and the RAD51/HR function. ...

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        COVID-19 in Ethiopia: A geospatial analysis of vulnerability to infection, case severity and death

        COVID-19 has caused a global public health crisis affecting most countries, including Ethiopia, in various ways. This study maps the vulnerability to infection, case severity and likelihood of death from COVID-19 in Ethiopia. Thirty-eight potential indicators of vulnerability to COVID-19 infection, case severity and likelihood of death, identified based on a literature review and the availability of nationally representative data at a low geographic scale, were assembled from multiple sources for geospatial analysis. Geospatial analysis techniques were applied to produce maps showing the vulnerability to infection, case severity and likelihood of death in Ethiopia at a spatial resolution of 1 km×1 km. ...

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        Worries, 'weirdos', neighborhoods and knowing people: a qualitative study with children and parents regarding children's independent mobility

        This study involved focus groups with 132 children and 12 parents in primary and secondary school in Victoria to explore children's independent mobility. ...

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        Recurrent MET fusion genes represent a drug target in pediatric glioblastoma

        We identified previously unidentified gene fusions involving the MET oncogene in pediatric glioblastoma ...

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        The influence of the neighborhood physical environment on early child health and development: A review and call for research

        This review examines evidence of the association between the neighborhood built environment, green spaces and outdoor home area, and early (0-7 years) child... ...

        Research

        Emerging Directions and New Challenges

        In this chapter we provide a brief summary of the key themes of the book, identify emerging directions and challenges in life course theory and data designs and highlight some policy challenges for researchers going forward. © 2022, The Author(s). ...

        Research

        Universal child health and early education service use from birth through Kindergarten and developmental vulnerability in the Preparatory Year (age 5 years) in Tasmania, Australia

        This study investigated patterns of universal health and education service use from birth through Kindergarten (age 4 years) and estimated associations between cumulative risk and service use patterns, and between service use patterns and children's developmental vulnerability in the Preparatory Year (age 5 years). ...

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