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        “We don’t want you to come in and make a decision for us”: Traversing cultural authority and responsive regulation in Australian child protection systems

        The Ngulluk Koolunga Ngulluk Koort (Our Children Our Heart) project conducted extensive Elder and community consultation to develop principles and practice recommendations for child protection governance in Western Australia. We explore these principles and practice recommendations and highlight the need for culturally safe community consultation and governance with a focus on repairing damage incurred by the Aboriginal and Torres Strait Islander community from past child protection policies. ...

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        Recurrent MET fusion genes represent a drug target in pediatric glioblastoma

        We identified previously unidentified gene fusions involving the MET oncogene in pediatric glioblastoma ...

        Research

        Longitudinal impact of the Cyber Friendly Schools program on adolescents' cyberbullying behavior

        Cyber Friendly Schools program was associated with significantly greater declines in the odds of involvement in cyber-victimization and perpetration ...

        Research

        FeBRILe3– Fever, Blood cultures and Readiness for discharge in Infants Less than 3 months’ old

        Tom Snelling T BMBS DTMH GDipClinEpid PhD FRACP Head, Infectious Disease Implementation Research 08 6319 1817 tom.snelling@telethonkids.org.au Head, Infectious Disease Implementation Research Professor Tom Snelling is Head of the Infectious Disease ...

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        Early life arsenic exposure and acute and long-term responses to influenza A infection in mice

        Exposure to arsenic in early life has been shown to increase the rate of respiratory infections during infancy, reduce childhood lung function, and increase... ...

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        Factors influencing the assessment of lung function in mice with influenza-induced lung disease

        The constant-phase model (CPM) is commonly fit to respiratory system input impedance (Z rs) to estimate lung mechanics. ...

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        The effects of acamprosate on maternal and neonatal outcomes in a mouse model of alcohol use disorders

        Despite the teratogenic effects of alcohol, little is known about the safety of pharmacotherapies such as acamprosate for the treatment of alcohol use disorders in pregnancy. The aims of this study were to investigate, in a mouse model, the effects of maternally administered acamprosate on maternal and neonatal health, offspring neurodevelopment and behaviour, as well as examine whether acamprosate reduces the neurological harm associated with alcohol consumption in pregnancy. ...

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        Editorial overview: Endocrine and metabolic adaptations to extreme environments: Living life to the extreme – insights into the limits of life and transitions to disease

        The need to understand responses to extreme environments has prompted this edition of Current Opinion in Endocrine and Metabolic Research ...

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        Mouse Lung Structure and Function after Long-Term Exposure to an Atmospheric Carbon Dioxide Level Predicted by Climate Change Modeling

        Climate change models predict that atmospheric carbon dioxide [CO2] levels will be between 700 and 900 ppm within the next 80yrs. In this study we aimed to assess the respiratory structure and function effects of long-term exposure to 890ppm CO2 from preconception to adulthood using a mouse model. ...

        Research

        Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

        Our study provides evidence that OT-82 is a promising new therapeutic strategy for a broad spectrum of high-risk pediatric acute lymphoblastic leukemia ...

        Research

        Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours

        The class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway. ...

        Research

        The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

        Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders. ...

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