Cerebral palsy (CP) is a lifelong physical disability, resulting from maldevelopment or damage to the developing brain. All children with CP have a disorder of movement and posture, but this is often accompanied by disorders of intellect, sensation, behaviour and epilepsy. Long-standing CP registers and surveillance systems estimate the prevalence of CP as approximately 2 per 1000 live births; however variations are seen over time and in different regions of the world. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Understanding how and why these disorders co-occur has important implications for diagnosis, treatment, and prognosis, as well as for developing fundamental... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

This study has shown a gender difference in the relationship between passive smoking exposure since birth and HDL-C in late adolescence. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

Our results reveal the complexity of Leishmania donovani evolution in the Indian subcontinent in response to drug treatment ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

In this study of hand shape analysis, we introduce the reader already familiar with the field of twin research to the potential utility of geometric... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• April 2013

17β-Estradiol is important in maintaining bone structure, and regulation of its synthesis plays an important role in the development of postmenopausal... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• September 2011

The Australian Autism Biobank was initiated to establish a large-scale repository of biological samples and detailed clinical information about children diagnosed with ASD ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

We confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

We investigated the prevalence of UDT and examined rates of surgery and age at surgery in an Australian population. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Asthma exacerbations are heterogeneous conditions that involve the complex interplay between environmental exposures and innate and adaptive immune function ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• August 2012

Surgical resection of cancer remains the frontline therapy for millions of patients annually, but post-operative recurrence is common, with a relapse rate of around 45% for non-small cell lung cancer. The tumour draining lymph nodes (dLN) are resected at the time of surgery for staging purposes, and this cannot be a null event for patient survival and future response to immune checkpoint blockade treatment. This project investigates cancer surgery, lymphadenectomy, onset of metastatic disease, and response to immunotherapy in a novel model that closely reflects the clinical setting. In a murine metastatic lung cancer model, primary subcutaneous tumours were resected with associated dLNs remaining intact, completely resected or partially resected. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021