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        An introduction to clinical trial design

        This manuscript will give a brief overview of clinical trial design including the strengths and limitations of various approaches ...

        Research

        Changing Prevalence of Lower Airway Infections in Young Children with Cystic Fibrosis

        Aspergillus species and P. aeruginosa are commonly present in the lower airways from infancy ...

        Research

        An integrative analysis of non-coding regulatory DNA variations associated with autism spectrum disorder

        Overall, we found that the regulatory variants in autism spectrum disorder cases were enriched in ASD-risk genes and genes involved in fetal neurodevelopment ...

        Research

        Bronchopulmonary dysplasia: Rationale for a pathophysiological rather than treatment based approach to diagnosis

        This review describes the evolution of bronchopulmonary dysplasia definitions, evaluates the benefits and limitations of each approach ...

        Research

        Eighth annual conference of in VIVO planetary health: From challenges to opportunities

        Here, we present the abstracts and proceedings of our 8th annual conference, held in Detroit, Michigan in May 2019, themed "From Challenges, to Opportunities" ...

        Research

        Molecular Epidemiology of Noninvasive and Invasive Group A Streptococcal Infections in Cape Town

        There is low coverage of the multivalent M protein vaccine in our setting, emphasizing the need to reformulate the vaccine to improve coverage ...

        Research

        Season, terrestrial ultraviolet radiation, and markers of glucose metabolism in children living in Perth, Western Australia

        Increased safe sun exposure in winter therefore represents a plausible means of reducing fasting blood sugar in children with obesity ...

        Research

        Early-life exposure to electronic cigarettes: cause for concern

        There are a multitude of ways that, with respect to early-life exposures and health, electronic nicotine delivery systems are a cause for concern ...

        Research

        Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation

        These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease prevention ...

        Research

        Caregiver’s attitudes, beliefs, and experiences for influenza vaccination in Australian children with medical comorbidities

        Influenza vaccination recommendation by children’s hospital physicians and previous vaccine receipt in hospital was associated with vaccine uptake ...

        Research

        Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic Response

        Despite low ERBB4 mRNA in glioblastoma, the functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target ...

        Research

        Sleep disturbances in Rett syndrome: Impact and management including use of sleep hygiene practices

        Attention to sleep hygiene remains an important management strategy for sleep problems in Rett syndrome ...

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