The authors assessed the impact of including preschool‐aged children with a history of preterm birth, early life wheeze, asthma diagnoses and/or recent respiratory symptoms in healthy reference ranges for respiratory impedance using the forced oscillation technique (FOT). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• April 2018

Mannitol challenge tests are used clinically to diagnose asthma and, in particular, exercise-induced broncoconstriction (EIB) in adults and children above 6... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• November 2013

Vitamin D deficiency is a global public health problem and has been associated with an increased incidence and severity of many diseases including diseases... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

Investigators: Nicole Burger Assisted reproductive technologies have been associated with adverse perinatal outcomes, however subfertile women who conceive naturally also have increased adverse perinatal outcomes. We aimed to classify couples ...

• 1. Telethon Kids Institute
• Projects

There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

Early aberrant antibody responses, aeroallergen sensitised people, subclinical bacterial infection ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• January 2010

Here, we report on a model that does not use Th2-skewing adjuvants and yet achieves sensitization solely via the nasal mucosa. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

Dysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

These findings suggest the utility of specific FOT outcomes is dependent on the respiratory disease being assessed ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

• 1. Telethon Kids Institute
• Projects

The immunological changes underpinning acquisition of remission (also called sustained unresponsiveness) following food immunotherapy remain poorly defined. Limited access to effective therapies and biosamples from treatment responders has prevented progress. Probiotic peanut oral immunotherapy is highly effective at inducing remission, providing an opportunity to investigate immune changes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

This large population-based study suggests a significant healthcare burden associated with influenza in children with a range of chronic lung diseases ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019