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        Understanding leishmaniasis through HLA

        Jenefer Blackwell JM BSc with First Class Honours, PhD, DSc, FMedSci, FAA Head, Genetics & Health Jenefer.Blackwell@telethonkids.org.au Head, Genetics & Health Professor Blackwell's major interest is genetic epidemiology of infectious disease, and ...

        Research

        Genetics of Otitis Media

        Sarra Jenefer Jamieson Blackwell SE JM BSc (Hons) MSc PhD BSc with First Class Honours, PhD, DSc, FMedSci, FAA Senior Research Fellow Head, Genetics & Health sarra.jamieson@telethonkids.org.au Jenefer.Blackwell@telethonkids.org.au Senior Research ...

        Research

        Behavioural and neuropsychological outcomes in children exposed in utero to maternal labour epidural analgesia

        Recent studies report conflicting results regarding the relationship between labour epidural analgesia (LEA) in mothers and neurodevelopmental disorders in their offspring. We evaluated behavioural and neuropsychological test scores in children of mothers who used LEA. ...

        Research

        How we measure language skills of children at scale: A call to move beyond domain-specific tests as a proxy for language

        The aim of this research note is to encourage child language researchers and clinicians to give careful consideration to the use of domain-specific tests as a proxy for language; particularly in the context of large-scale studies and for the identification of language disorder in clinical practice. ...

        Research

        Characterising the Early Presentation of Motor Difficulties in Autistic Children

        This study aimed to explore the rates of motor difficulties in children from the Australian Autism Biobank, and how early motor concerns impacted on children functionally. ...

        Research

        Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis

        Our data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans ...

        Research

        Epigenetics in infectious diseases

        Viruses, bacteria, and parasites have developed strategies to invade and establish long-term infections in their hosts. ...

        Research

        Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil

        Here we examined single nucleotide polymorphisms (SNPs) in these genes as risk factors for cutaneous (CL) and mucosal leishmaniasis (ML), and leishmaniasis... ...

        Research

        Insights into the possible role of IFNG and IFNGR1 in Kala-azar and Post Kala-azar Dermal Leishmaniasis in Sudanese patients

        Uniformly low expression of IFN and IFNGR1 in PKDL skin biopsies could explain parasite persistence ...

        Research

        Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expression

        Here we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei. ...

        Research

        Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?

        The current study sought to determine whether gestational hypertension and pre-eclampsia are associated with neurocognitive outcomes in middle childhood. ...

        Research

        A preliminary study of fetal head circumference growth in Autism Spectrum Disorder

        Fetal head circumference (HC) growth was examined prospectively in children with autism spectrum disorder (ASD). ...

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