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        A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma

        We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma ...

        Research

        High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

        Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities ...

        Research

        The evolution of local food environments within established neighbourhoods and new developments in Perth, Western Australia

        People living in new developments, and low SES areas of Perth, may be disadvantaged with poorer access to healthy food and greater exposure to unhealthy food outlets ...

        Research

        Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

        Systems biology and innovative data integration can provide fresh insights into the molecular ontogeny of the first week of life ...

        Research

        Concurrent developmental course of sleep problems and emotional/behavioral problems in childhood and adolescence as reflected by the dysregulation profile

        Findings provide evidence for a strong association in the development of sleep problems and difficulties of dysregulation with emotion, cognition, and aggression ...

        Research

        Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing

        Asthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes ...

        Research

        Evening and night work schedules and children's social and emotional well-being

        The findings show that both mothers’ and fathers’ evening and night work schedules are linked to an increase in children's externalizing and internalizing behavior ...

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        Potential for molecular testing for group a streptococcus to improve diagnosis and management in a high-risk population: A prospective study

        Implementation of molecular testing could improve antibiotic use in this high-burden setting ...

        Research

        HLA-DR Class II expression on myeloid and lymphoid cells in relation to HLA-DRB1 as a genetic risk factor for visceral leishmaniasis

        To understand how HLA-DR contributes to disease pathogenesis, we examined expression at the protein level in circulating myeloid and lymphoid cells of VL patients ...

        Research

        Influenza Epidemiology, Vaccine Coverage and Vaccine Effectiveness in Children Admitted to Sentinel Australian Hospitals in 2017

        Significant influenza-associated morbidity was observed in 2017 in Australia. Vaccine coverage and antiviral use was inadequate. ...

        Research

        Trends and predictors of extreme preterm birth: Western Australian population-based cohort study

        First study to show that the increase in extreme preterm birth in high-income jurisdiction is no longer evident after medical terminations and birth defects are excluded ...

        Research

        Determinants for progression from asymptomatic infection to symptomatic visceral leishmaniasis: A cohort study

        We confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects ...

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