This study investigates the different patterns of relapse in patients with central nervous system mixed malignant germ cell tumors - treated with chemotherapy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015

Functional role of CTGF in altering disease progression in a lymphoid malignancy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

We report a term male with congenital acute erythroleukemia who achieved sustained remission with low-dose cytosine arabinoside alone ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Medulloblastoma is the most common malignant childhood brain tumor, and 5-year overall survival rates are as low as 40% depending on molecular subtype, with new therapies critically important. As radiotherapy and chemotherapy act through the induction of DNA damage, the sensitization of cancer cells through the inhibition of DNA damage repair pathways is a potential therapeutic strategy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Inhalation of airborne asbestos fibres causes several diseases. These include asbestosis, lung cancer, malignant mesothelioma as well as pleural effusion... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

This article summarizes data from collaborative group and institutional trials that have advanced the science of pediatric brain tumors. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015

Childhood acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and brain tumors (CBTs) are the leading cause of cancer death in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• February 2012

Tumor cell death potentially engages with the immune system. However, the efficacy of anti-tumor chemotherapy may be limited by tumor-driven... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• August 2009

This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

In this study, we report the case of an adolescent NMC patient presenting with severe facial pain, proptosis and visual impairment due to a mass arising from... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015