There is no consensus on how best to measure responses to interventions among children and adults with cystic fibrosis (CF). We have systematically reviewed and summarised the characteristics and measurement properties of tests and tools that have been used to capture outcomes in studies among people with CF, including their reliability, validity and responsiveness. This review is intended to guide researchers when selecting tests or tools for measuring treatment effects in CF trials. A consensus set of these tests and tools could improve consistency in how outcomes are captured and thereby facilitate comparisons and synthesis of evidence across studies. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

The authors assessed the impact of including preschool‐aged children with a history of preterm birth, early life wheeze, asthma diagnoses and/or recent respiratory symptoms in healthy reference ranges for respiratory impedance using the forced oscillation technique (FOT). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• April 2018

To evaluate the effectiveness of maternal pertussis vaccination for preventing pertussis infections in Aboriginal and Torres Strait Islander infants under seven months of age. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

Treatment for pulmonary exacerbations of cystic fibrosis (CF) can produce a range of positive and negative outcomes. Understanding which of these outcomes are achievable and desirable to people affected by disease is critical to agreeing to goals of therapy and determining endpoints for trials. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

To determine the contribution of RSV to the subsequent development of severe asthma in different subgroups of children at risk of severe RSV disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Respiratory viruses, particularly respiratory syncytial virus and human metapneumovirus, are major contributors to pneumonia in Australian children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

We will investigate the relationship between PCV coverage and VT carriage among undervaccinated children in Asia and the Pacific ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

The aim of this study was to assess the relationship between dust levels and health in Indigenous children in Western Australia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

A wet cough in a child for more than four weeks could indicate infection in the lungs. The wet cough is caused by mucus in the airway. The mucus becomes infected with bacteria and causes airway inflammation that can progress to permanent lung damage known as bronchiectasis. ...

• 1. Telethon Kids Institute
• Our research
• Research Topics

In the absence of an established gold standard, an understanding of the testing cycle from individual exposure to test outcome report is required to guide the correct interpretation of SARS-CoV-2 reverse transcriptase real-time polymerase chain reaction (RT-PCR) results and optimise the testing processes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Using linked data, we describe changes in respiratory virus testing among children born in Western Australia in 1996-2012 ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• June 2017