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        301-312 of 785 results for 'asthma'

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        Narrowband UVB phototherapy reduces TNF production by B-cell subsets stimulated via TLR7 from individuals with early multiple sclerosis

        At the end of a 60-day course of narrowband UVB phototherapy, administered to individuals with early multiple sclerosis, there were changes in the relative proportions of circulating B-cell subsets. This study investigated phototherapy-associated changes to cytokine responses of B cells when exposed to a TLR7 ligand. ...

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        Pregnancy Induces a Steady-State Shift in Alveolar Macrophage M1/M2 Phenotype That Is Associated With a Heightened Severity of Influenza Virus Infection

        Pregnancy is associated with an alternatively activated phenotype of alveolar macrophage before infection ...

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        Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

        The mutant Der p 2 had altered structure and reduced ability to stimulate pro-inflammatory responses and to bind IgE ...

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        Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific

        Chronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear ...

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        Ground zero—the airway epitheliumNew Page

        This chapter will discuss the structure of the airway highlighting the now broad number of cell types that comprise it ...

        Research

        Tracking of Vitamin D status from childhood to early adulthood and its association with peak bone mass

        There are moderate associations between vitamin D status measured in prepuberty, adolescence, and early adulthood ...

        Research

        Associations between respiratory and vascular function in early childhood

        The link between respiratory and vascular health is well documented in adult populations. Impaired lung function is consistently associated with thicker arteries and higher incidence of cardiovascular disease. However, there are limited data on this relationship in young children and the studies that exist have focussed on populations at high risk of cardiorespiratory morbidity. ...

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        Phenotypic, functional, and plasticity features of classical and alternatively activated human macrophages

        Human peripheral blood monocytes were differentiated into uncommitted macrophages (M0) and then polarized to M1 and M2 phenotypes using LPS/IFN-gamma... ...

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        Immune modulation by UV: Role of vitamin D

        In this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented. ...

        Research

        Reduced rhinovirus-specific antibodies are associated with acute exacerbations of chronic obstructive

        Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are often linked to respiratory infections. ...

        Research

        The Role of Subinhibitory Concentrations of Daptomycin and Tigecycline in Modulating Virulence in Staphylococcus aureus

        Staphylococcus aureus (S. aureus) infections are notoriously complicated by the ability of the organism to grow in biofilms and are difficult to eradicate with antimicrobial therapy. ...

        Research

        Making a Killer: Selecting the Optimal Natural Killer Cells for Improved Immunotherapies

        Over the past 20 years natural killer (NK) cell-based immunotherapies have emerged as a safe and effective treatment option for patients with relapsed or refractory leukemia. Unlike T cell-based therapies, NK cells harbor an innate capacity to eliminate malignant cells without prior sensitization and can be adoptively transferred between individuals without the need for extensive HLA matching. ...

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