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        Tricho-hepatic-enteric syndrome (THES) without intractable diarrhoea

        We report an 8 year old girl who was diagnosed with THES by the Undiagnosed Disease Program-WA with compound heterozygous pathogenic variants in SKIV2L ...

        Research

        High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

        Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities ...

        Research

        Concurrent developmental course of sleep problems and emotional/behavioral problems in childhood and adolescence as reflected by the dysregulation profile

        Findings provide evidence for a strong association in the development of sleep problems and difficulties of dysregulation with emotion, cognition, and aggression ...

        Research

        Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

        Systems biology and innovative data integration can provide fresh insights into the molecular ontogeny of the first week of life ...

        Research

        Children with East Asian-Born Parents Have an Increased Risk of Allergy but May Not Have More Asthma in Early Childhood

        Children of East Asian ancestry born in Australia have a higher burden of most allergic diseases in the first 6 years of life, whereas asthma may follow a different pattern ...

        Research

        How body composition influences hearing status by mid-childhood and mid-life: The Longitudinal Study of Australian Children

        Concurrent adiposity and decade-long BMI trajectories showed small, but clear, associations with poor hearing in mid-life women ...

        Research

        Discovery of Transcription Factors Novel to Mouse Cerebellar Granule Cell Development Through Laser-Capture Microdissection

        This study provides an initial insight into the TFs of cerebellar granule cells that might be important for development ...

        Research

        Metabolic and Psychological Impact of a Pragmatic Exercise Intervention Program in Adolescent and Young Adult Survivors of Pediatric Cancer-Related Cerebral Insult

        Adolescent and young adult survivors of childhood brain tumors and cranial irradiation should be screened for metabolic and psychological well-being ...

        Research

        Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern Australia

        Prevalence of skin sores and scabies in remote Australian Aboriginal communities remains unacceptably high, with Group A Streptococcus (GAS) the dominant pathogen. We aim to better understand the drivers of GAS transmission using mathematical models. ...

        Research

        Attenuated psychophysiological reactivity following single-session group imagery rescripting versus verbal restructuring in social anxiety disorder

        The current study highlights the specificity of brief imagery-based interventions in influencing psychophysiological reactivity in social anxiety disorder ...

        Research

        REACH: study protocol of a randomised trial of rehabilitation very early in congenital hemiplegia

        Congenital hemiplegia is the most common form of cerebral palsy (CP). Children with unilateral CP show signs of upper limb asymmetry by 8 months corrected age (ca) but are frequently not referred to therapy until after 12 months ca. This study compares the efficacy of infant-friendly modified constraint-induced movement therapy (Baby mCIMT) to infant friendly bimanual therapy (Baby BIM) on upper limb, cognitive and neuroplasticity outcomes in a multisite randomised comparison trial. ...

        Research

        Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor

        We report on 3 children treated with vismodegib who developed widespread growth plate fusions that persist long after cessation of therapy. ...

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