CDKL5 Deficiency Disorder (CDD) is a rare, X-linked dominant condition that causes a developmental and epileptic encephalopathy (DEE). The incidence is between ~ 1:40,000 and 1:60,000 live births. Pathogenic variants in CDKL5 lead to seizures from infancy and severe neurodevelopmental delay. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

Respiratory disease is a leading cause of morbidity, mortality, and poor quality of life in children with cerebral palsy (CP). This study describes the prevalence of CP-related respiratory disease and the non-modifiable risk factors for respiratory-related hospital admissions in the Aotearoa New Zealand population. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

Preterm birth is a global public health problem with a significant burden on the individuals affected. The study aimed to extend current research on preterm birth prognostic model development by developing and internally validating models using machine learning classification algorithms and population-based routinely collected data in Western Australia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

KMT2A-rearranged acute lymphoblastic leukemia (ALL) in infants is an aggressive disease with 3-year event-free survival below 40%. Most relapses occur during treatment, with two thirds occurring within 1 year and 90% within 2 years after diagnosis. Outcomes have not improved in recent decades despite intensification of chemotherapy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

Anna Hunt AH DipTch, BEd Research Administrator 08 6319 1290 Anna.Hunt@telethonkids.org.au Research Administrator she/her/hers Anna Hunt is a Research Administrator with the Youth Mental Health team. Anna’s background is in teaching. She completed a ...

• 1. Telethon Kids Institute
• Projects
• Past projects

Larger samples of patients are needed to better understand if the differentiation between very early onset psychosis and early onset psychosis is justified ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

A systematic comparison of the cellular and molecular changes in neurons in vitro induced by low intensity magnetic stimulation at different frequencies. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• January 2014

Globally, life expectancy from birth increased from 61·7 years in 1980 to 71·8 years in 2015 ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• October 2016

A pre-emptive intervention for the autism spectrum disorder prodrome had no immediate treatment effect on early autism spectrum disorder symptoms ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019

Gut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

In this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

Research in psychopharmacology in children and adolescents is an area of growing interest with numerous newer modalities becoming available in recent years. Nevertheless, it still lags significantly behind research in adult psychopharmacology although, in the last decade, the gap is beginning to be bridged with FDA approval for newer agents for the paediatric age group. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023