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        Research

        Hierarchy and molecular properties of house dust mite allergens

        The allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity. ...

        Research

        Using Hawkes Processes to model imported and local malaria cases in near-elimination settings

        Developing new methods for modelling infectious diseases outbreaks is important for monitoring transmission and developing policy. In this paper we propose using semi-mechanistic Hawkes Processes for modelling malaria transmission in near-elimination settings. Hawkes Processes are well founded mathematical methods that enable us to combine the benefits of both statistical and mechanistic models to recreate and forecast disease transmission beyond just malaria outbreak scenarios. ...

        Research

        Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: a randomised controlled trial of PCV in Papua New Guinean infants

        Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting ...

        Research

        High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

        Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities ...

        Research

        Whither pertussis?

        This article discusses the rising prevalence of pertussis disease in countries which have switched to acellular vaccines. ...

        Research

        Geogenic PM10 exposure exacerbates responses to influenza infection

        This study aimed to determine whether chronic, low-dose exposure to geogenic particulate matter <10μm diameter (PM10) exacerbates viral infections of the... ...

        Research

        What do infectious diseases physicians do? A 2-week snapshot of inpatient consultative activities across Australia, New Zealand and Singapore

        We performed a 2-week prospective survey of formal ID physician activities related to direct inpatient care, encompassing 53 hospitals throughout Australia,... ...

        Research

        Multidrug-resistant tuberculosis in Western Australia, 1998-2012

        Our objective was to describe the epidemiology, clinical features, health care resource use, treatment and outcomes of multidrug-resistant tuberculosis... ...

        Research

        Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conjugate vaccine schedules

        In Australian remote communities, First Nations children with otitis media (OM)-related hearing loss are disproportionately at risk of developmental delay and poor school performance, compared to those with normal hearing. Our objective was to compare OM-related hearing loss in children randomised to one of 2 pneumococcal conjugate vaccine (PCV) formulations. ...

        Research

        A phase I clinical trial assessing the safety, tolerability, and pharmacokinetics of inhaled ethanol in humans as a potential treatment for respiratory tract infections

        Current treatments for respiratory infections are severely limited. Ethanol's unique properties including antimicrobial, immunomodulatory, and surfactant-like activity make it a promising candidate treatment for respiratory infections if it can be delivered safely to the airway by inhalation. Here, we explore the safety, tolerability, and pharmacokinetics of inhaled ethanol in a phase I clinical trial. ...

        Research

        Editorial: Vaccines and immunization services during the pandemic era and beyond

        Citation: Amponsah-Dacosta E, Fulurija A, Afum-Adjei Awuah A, Mathema S, Wariri O. Editorial: Vaccines and immunization services during the pandemic era and beyond. Front Health Serv. 2024;4. Keywords: COVID-19; equity; immunization; pandemic; ...

        Research

        Mapping tuberculosis prevalence in Ethiopia using geospatial meta-analysis\

        Reliable and detailed data on the prevalence of tuberculosis (TB) with sub-national estimates are scarce in Ethiopia. We address this knowledge gap by spatially predicting the national, sub-national and local prevalence of TB, and identifying drivers of TB prevalence across the country. ...

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