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        HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms

        HLA-A*32:01 is strongly associated with vancomycin-induced DRESS in a population of predominantly European ancestry ...

        Research

        Intraseason decline in influenza vaccine effectiveness during the 2016 southern hemisphere influenza season: A test-negative design study and phylogenetic assessment

        Overall, the 2016 influenza vaccine showed good protection against laboratory-confirmed infection among general practice patients ...

        Research

        Identification of an Esterase Isolated Using Metagenomic Technology which Displays an Unusual Substrate Scope and its Characterisation as an Enantioselective Biocatalyst

        Evaluation of an esterase annotated as 26D isolated from a marine metagenomic library is described ...

        Research

        AMEND study protocol: A case-control study to assess the long-term impact of invasive meningococcal disease in Australian adolescents and young adults

        This study aims to address this evidence gap by assessing the clinical, physical, neurocognitive, economic and societal impact of invasive meningococcal disease ...

        Research

        Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

        IL7 and glucocorticoids coordinately drive aberrant activation of PIM1 and suggests that T-ALL and T-LBL patients could benefit from PIM inhibition ...

        Research

        Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipients

        Our data illustrate that rhinovirus infection is capable of infecting upper and lower airway epithelial cells, driving cell death and inflammation ...

        Research

        Improvement in Psychosocial Outcomes in Children with Type 1 Diabetes and Their Parents Following Subsidy for Continuous Glucose Monitoring

        Introduction of subsidized CGM showed early improvement in psychosocial and glycemic outcomes in patients and their families in Western Australia ...

        Research

        Choosing primary endpoints for clinical trials of health care interventions

        This narrative review describes the evolution, range and relative strengths and weaknesses of endpoints used in late phase trials ...

        Research

        Coffee and tea consumption during pregnancy and risk of childhood acute myeloid leukemia: A Childhood Leukemia International Consortium (CLIC) study

        We investigated the potential association of maternal coffee and tea consumption during pregnancy with childhood acute myeloid leukemia risk ...

        Research

        Sun-immune connection

        Exposure to ultraviolet radiation damages skin cell DNA but skin cancers develop because ultraviolet radiation also affects the immune system ...

        Research

        Availability and administration of benzathine penicillin G for the prevention of rheumatic fever in Africa: Report of the Working Group on Penicillin

        Benzathine penicillin G availability should be addressed and African health workers’ knowledge and practices need to be augmented ...

        Research

        Paediatric asylum seekers in Western Australia: Identification of adversity and complex needs through comprehensive refugee health assessment

        Paediatric asylum seekers have complex trauma backgrounds with exposure to multiple adverse events within disrupted family units ...

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