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        Linking a pharmaceutical claims database with a birth defects registry to investigate birth defect rates of suspected teratogens

        Data linkage of population administrative data is being investigated as a tool for pharmacovigilance in pregnancy in Australia. ...

        Research

        Rationale for access to public sector information

        On the back of the growing capacity of networked digital information technologies to process and visualise large amounts of information in a timely, efficient a ...

        Research

        Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conjugate vaccine schedules

        In Australian remote communities, First Nations children with otitis media (OM)-related hearing loss are disproportionately at risk of developmental delay and poor school performance, compared to those with normal hearing. Our objective was to compare OM-related hearing loss in children randomised to one of 2 pneumococcal conjugate vaccine (PCV) formulations. ...

        Research

        Type 2 diabetes in children and adolescents across Australia and New Zealand: A 6‐year audit from The Australasian Diabetes Data Network (ADDN)

        To assess the clinical and demographic characteristics of children and adolescents across Australia and New Zealand (NZ) with type 2 diabetes. ...

        Research

        What doctors should consider before prescribing e-liquids for e-cigarettes

        Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

        Research

        Advanced glycation end products as predictors of renal function in youth with type 1 diabetes

        To examine if skin autofluorescence differed in early adulthood between individuals with type 1 diabetes and age-matched controls and to ascertain if sAF aligned with risk for kidney disease. ...

        Research

        LUMOS - Low and Intermediate Grade Glioma Umbrella Study of Molecular Guided TherapieS at relapse: Protocol for a pilot study

        Introduction Grades 2 and 3 gliomas (G2/3 gliomas), when combined, are the second largest group of malignant brain tumours in adults. The outcomes for G2/3 gliomas at progression approach the dismal outcomes for glioblastoma (GBM), yet there is a paucity of trials for Australian patients with relapsed G2/3 gliomas compared with patients with GBM. ...

        Research

        Off-label use of ondansetron in pregnancy in Western Australia

        There is an increasing trend to prescribe ondansetron although its safety for use in pregnancy has not been established. ...

        Research

        Privacy protectionism and health information: Is there any redress for harms to health?

        Health information collected by governments can be a valuable resource for researchers seeking to improve diagnostics, treatments and public health outcomes. ...

        Research

        Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

        These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC ...

        Research

        Trends in maternal and newborn health characteristics and obstetric interventions among Aboriginal and Torres Strait Islander mothers

        Trends in maternal demographic characteristics, pre-existing medical conditions, pregnancy complications and neonatal characteristics were examined. ...

        Research

        Interpretation of recent sudden infant death syndrome rates in Western Australia

        Data for recent years show a shift away from a classification of 'SIDS' towards a classification of 'unascertainable', particularly for Aboriginal infants. ...

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