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        Deciphering the Immunological Phenomenon of Adaptive Natural Killer (NK) Cells and Cytomegalovirus (CMV)

        Natural killer (NK) cells play a significant and vital role in the first line of defense against infection through their ability to target cells without prior sensitization. They also contribute significantly to the activation and recruitment of both innate and adaptive immune cells through the production of a range of cytokines and chemokines. In the context of cytomegalovirus (CMV) infection, NK cells and CMV have co-evolved side by side to employ several mechanisms to evade one another. ...

        Research

        Prenatal alcohol and tobacco use and the risk of depression in offspring at age of 17 years: findings from the Raine Study

        Prenatal alcohol and tobacco exposures have been associated with adverse mental health consequences in offspring. The objective of this study was to test the associations between maternal prenatal alcohol and tobacco exposures and depressive symptoms in the offspring, adjusting for a wide range of potential confounders. ...

        Research

        Associations of prenatal alcohol exposure and offspring harmful alcohol use: findings from the Raine Study

        Epidemiological evidence suggests offspring exposed to prenatal alcohol are at increased risk of alcohol use disorders in adulthood. The evidence on the risk of developing harmful alcohol use in adolescence is less clear. ...

        Research

        CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: Study protocol for a randomised controlled trial

        This study will assess the effect of adjunctive clindamycin on patient-centred outcomes in severe, toxin-mediated S. aureus infections ...

        Research

        Personalized transcriptomics reveals heterogeneous immunophenotypes in children with viral bronchiolitis

        Dysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants ...

        Research

        Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes

        These findings suggest the utility of specific FOT outcomes is dependent on the respiratory disease being assessed ...

        Research

        Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

        The WHF echocardiographic criteria enable reproducible categorisation of echocardiograms as definite RHD versus no or borderline RHD ...

        Research

        Effect of combining pre-exercise carbohydrate intake and repeated short sprints on the blood glucose response to exercise in young individuals with Type 1 diabetes

        When carbohydrates are ingested prior to moderate-intensity exercise, adding repeated sprints is not significantly detrimental to glycaemic management ...

        Research

        Indigenous compared with non-Indigenous Australian patients at entry to specialist palliative care: Cross-sectional findings from a multi-jurisdictional dataset

        Indigenous patients are substantially underrepresented in care by services participating in the nationwide specialist palliative care ...

        Research

        Is sport an untapped resource for recovery from first episode psychosis? A narrative review and call to action

        Sport-based interventions could be an opportunity to provide intervention to individuals recovering from their first psychotic episode ...

        Research

        Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndrome

        Since B cells are increasingly targeted by MS therapies, the effects of narrowband UVB phototherapy in people with MS should be investigated further ...

        Research

        Impact of social disadvantage on cerebral palsy severity

        In Australia, socio-economic disadvantage at birth impacts adversely on cerebral palsy severity at age 5 years ...

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