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        Analysis of glucose responses to automated insulin suspension with sensor-augmented pump therapy

        The advent of sensor-augmented pump therapy with a low-glucose suspend (LGS) function. ...

        Research

        House dust mite allergens in asthma and allergy

        IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against ...

        Research

        Investigating the walkability of primary, secondary and K-12 schools across metropolitan Perth, Western Australia

        Having a walkable built environment is important to encourage active school transport. The aim of this study was to measure the walkability of all Perth, Western Australian schools and investigate whether differences in walkability exist by school type, socioeconomic status and/or subregion.  ...

        Research

        Effect of different lung recruitment strategies and airway device on oscillatory mechanics in children under general anaesthesia

        Atelectasis has been reported in 68 to 100% of children undergoing general anaesthesia, a phenomenon that persists into the recovery period. Children receiving recruitment manoeuvres have less atelectasis and fewer episodes of oxygen desaturation during emergence. The optimal type of recruitment manoeuvre is unclear and may be influenced by the airway device chosen. ...

        Research

        Exercise training improves vascular function and secondary health measures in survivors of pediatric oncology related cerebral insult

        This study demonstrates that exercise is achievable and has positive effects on vascular function, submaximal fitness, local strength and physical activity in a population of AYA survivors of pediatric oncology related cerebral insult ...

        Research

        Influenza vaccination in pregnancy among a group of remote dwelling Aboriginal and Torres Strait Islander mothers in the Northern Territory

        We examined uptake of inactivated influenza vaccination in pregnancy and report adverse birth outcomes amongst a predominantly unvaccinated group ...

        Research

        Botulinum toxin and surgical intervention in children and adolescents with cerebral palsy: who, when and why do we treat?

        This audit aimed to increase understanding of the long-term outcomes of evidence-based medical and surgical interventions to improve gross motor function in children and adolescents with Cerebral Palsy. ...

        Research

        The plural of anecdote is not data, please mind the gap

        The COVID-19 pandemic introduced challenges to everyone in society but particularly so to every aspect of medical practice. It is bewildering how quickly the profession has had to respond to rapidly changing clinical landscape. Our well-established methods involve collecting and analyzing data to generate an evidence base which is then disseminated and implemented into routine clinical practice. ...

        Research

        Association between respiratory syncytial viral disease and the subsequent risk of the first episode of severe asthma in different subgroups of high-risk Australian children: a whole-of-population-based cohort study

        To determine the contribution of RSV to the subsequent development of severe asthma in different subgroups of children at risk of severe RSV disease. ...

        Research

        Echinocandins in Pediatric Invasive Candidiasis and the Challenges of Antifungal Use in Children

        In pediatric invasive candidiasis (IC), epidemiology and risk factors differ compared to adults. Furthermore, the use of antifungals in children is challenging and requires consideration of availability and tolerability of formulations, pharmacokinetic and pharmacodynamic variations, and safety in different age groups. ...

        Research

        Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy and haemopoietic stem cell transplant recipients, 2021

        Antifungal agents can have complex dosing and the potential for drug interaction, both of which can lead to subtherapeutic antifungal drug concentrations and poorer clinical outcomes for patients with haematological malignancy and haemopoietic stem cell transplant recipients. Antifungal agents can also be associated with significant toxicities when drug concentrations are too high. ...

        Research

        Reference values for spirometry and their use in test interpretation: A Position Statement from the Australian and New Zealand Society of Respiratory Science

        The ANZSRS recommends the adoption of the Global Lung Function Initiative (GLI) 2012 spirometry reference values throughout Australia and New Zealand ...

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