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        337-348 of 590 results for 'aboriginal respiratory'

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        Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

        Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 participants, we identified 1,020 independent association signals implicating 559 genes supported by ≥2 criteria from a systematic variant-to-gene mapping framework. These genes were enriched in 29 pathways. Individual variants showed heterogeneity across ancestries, age and smoking groups, and collectively as a genetic risk score showed strong association with COPD across ancestry groups. ...

        Research

        COCOON: Virus transmission, immunity, and family wellbeing during COVID-19

        Asha Desiree Stephen Susan Bowen Silva Stick Prescott AC DS SM SL BA MBBS DCH FRACP PhD GAICD MBBS, FRACP, MPH, PhD MB BChir PhD MRCP FRACP MBBS BMedSci PhD FRACP Team Lead, Healthy Skin and ARF Prevention Co-Head, The ORIGINS Project Head, P4 ...

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        Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conjugate vaccine schedules

        In Australian remote communities, First Nations children with otitis media (OM)-related hearing loss are disproportionately at risk of developmental delay and poor school performance, compared to those with normal hearing. Our objective was to compare OM-related hearing loss in children randomised to one of 2 pneumococcal conjugate vaccine (PCV) formulations. ...

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        Cord blood Streptococcus pneumoniae-specific cellular immune responses predict early pneumococcal carriage in high-risk infants in Papua New Guinea

        We aimed to explore whether newborns in high-risk areas have pre-existing pneumococcal-specific cellular immune responses that effects early acquisition. ...

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        Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea

        Vaccination trials in high endemicity areas are needed to provide evidence and guidance on idea strategies to protect children in these areas against infections ...

        Research

        Perinatal risk factors associated with skin infection hospitalisation in Western Australian Aboriginal and Non-Aboriginal children

        We have quantified the relative influence of perinatal risk factors associated with skin infection hospitalisations in WA children ...

        Research

        Australian trachoma surveillance annual report, 2013

        National Trachoma Surveillance and Reporting Unit to collate, analyse and report trachoma prevalence data and document trachoma control strategies in Australia ...

        Research

        Effectiveness of a 3 + 0 pneumococcal conjugate vaccine schedule against invasive pneumococcal disease among a birth cohort of 1.4 million children in Australia

        Our population-based cohort study demonstrates that >90% coverage in the first year of a universal 3 + 0 PCV program provided high population-level protection ...

        Research

        Influenza vaccination in pregnancy among a group of remote dwelling Aboriginal and Torres Strait Islander mothers in the Northern Territory

        We examined uptake of inactivated influenza vaccination in pregnancy and report adverse birth outcomes amongst a predominantly unvaccinated group ...

        Research

        Pneumococcal conjugate vaccination at birth in a high-risk setting: No evidence for neonatal T-cell tolerance

        Concerns about the risk of inducing immune deviation-associated "neonatal tolerance" as described in mice have restricted the widespread adoption... ...

        Research

        A process and impact evaluation of use of a Powered Wheelchair Standing Device by boys with Duchenne muscular dystrophy

        Graham Jenny Peter Hall Downs Jacoby GL JA PJ BAppSci PhD CRFS FANZSRS FThorSoc FERS BApplSci (physio) MSc PhD BA (Hons) MSc Honorary Research Associate Program Head, Development and Disability Biostatistician 08 6319 1763 Jenny.Downs@ ...

        Research

        The epigenetic origin of alcohol-induced disorders: a cross-species study

        Alexander David Martyn Larcombe Martino Symons A DM MS BScEnv (Hons) PhD BSc PhD B.A. (Hons) PhD. Team Leader, Respiratory Environmental Health Head, Clinical Epigenetics Honorary Research Associate 08 6319 1672 David.Martino@telethonkids.org.au ...

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