Infant allergy is the most common early manifestation of an increasing propensity for inflammation and immune dysregulation in modern environments. Refined low-fibre diets are a major risk for inflammatory diseases through adverse effects on the composition and function of gut microbiota. This has focused attention on the potential of prebiotic dietary fibres to favourably change gut microbiota, for local and systemic anti-inflammatory effects. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

There is significant data to support the hypothesis that early life nutrition in the fetus, infant and young child can have profound effects on long-term health ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• October 2016

Maternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• August 2012

We compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New Guinea)... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

The human gut microbiome has increasingly been associated with autism spectrum disorder (ASD), which is a neurological developmental disorder, characterized by impairments to social interaction. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

Taking folic acid containing supplements prior to and during early pregnancy reduces the risk of neural tube defects. Neural tube defects occur prior to 28 days postconception, after which, there is no proven benefit of continuing to take folic acid. However, many women continue to take folic acid containing supplements throughout the pregnancy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

Egg allergy affects almost 1 in 10 Australian infants. Early egg introduction has been associated with a reduced risk in developing egg allergy; however, the immune mechanisms underlying this protection remain unclear. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

This study highlights an unpredicted potential risk factor for the development of food allergy, that is, D pteronyssinus allergens in breast milk ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Here, we report on a model that does not use Th2-skewing adjuvants and yet achieves sensitization solely via the nasal mucosa. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

The dramatic rise in early childhood allergic diseases indicates the specific vulnerability of the immune system to early life environmental changes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Strategies to prevent early-life food allergen sensitisation prior to commencement of solid foods are needed and should be the focus of future research ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

We have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019