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        Air Trapping on Chest CT Is Associated with Worse Ventilation Distribution in Infants with Cystic Fibrosis

        In school-aged children with cystic fibrosis (CF) structural lung damage assessed using chest CT is associated with abnormal ventilation distribution. ...

        Research

        A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors

        In this. i study the MTD and RP2D, safety, PK, and preliminary activity of single-agent ribociclib were investigated in patients with neuroblastoma. ...

        Research

        Ngulluk Koolunga Ngulluk Koort (Our Children, Our Heart) Project

        Investigators: Albert McNamara, Allan Kickett Snr, Brad Farrant, Carol Michie, Carrington Shepherd, Charmaine Pell, Cheryl Kickett-Tucker, Clair Scrine, Doris Hill, Fiona Stanley, Glenn Pearson, Kerry Hunt, Larissa Perry, Michael Wright, Millie ...

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        A phase IIIB, randomized, controlled, observer-blind study to evaluate safety and immunogenicity of GSK’s meningococcal ABCWY vaccine when administered in healthy adolescents and adults, previously primed with meningococcal ACWY vaccine (BOOST)

        Investigator: Peter Richmond Project description GSK is conducting a research study to evaluate its investigational, pentavalentmeningococcal vaccine, MenABCWY, which is based upon two licensed GSKmeningococcal vaccines, Menveo (MenACWY vaccine) and ...

        Research

        Effectiveness of pneumococcal conjugate vaccine against hospital admissions for pneumonia in Australian children

        Reductions in pneumonia-coded hospital admissions in unvaccinated children predominated in non-Aboriginal children with low incidence of pneumonia ...

        Research

        Evaluating a community-based early childhood education and development program in Indonesia: study protocol for a pragmatic cluster randomized controlled trial

        The aim of the trial is to evaluate a community-based early education and development program launched by the Government of Indonesia. ...

        Research

        Changes in thymic regulatory T-cell maturation from birth to puberty: Differences in atopic children

        We report vaccine efficacy against CIN3+ and adenocarcinoma in situ (AIS) in the end-of-study analysis of PATRICIA (PApilloma TRIal against Cancer In young... ...

        Research

        Locomotor and robotic assistive gait training for children with cerebral palsy

        To determine if robotic assisted gait training (RAGT) using surface muscle electrical stimulation and locomotor training enhances mobility outcomes when compared to locomotor training alone in children with cerebral palsy (CP). Forty children (18 females, 22 males; mean age 8y 1mo, SD 2y 1mo; range 5y 1mo-12y 11mo) with CP in Gross Motor Function Classification System levels (GMFCS) III, IV, and V were randomly assigned to the RAGT and locomotor training (RAGT+LT) group or locomotor training only group (dosage for both: three 1-hour sessions a week for 6 weeks). Outcomes were assessed at baseline T1 (week 0), post-treatment T2 (week 6), and retention T3 (week 26). ...

        Research

        Incidence of childhood onset type 1 diabetes in Western Australia from 1985 to 2016: Evidence for a plateau

        This study provides evidence for a possible plateauing in the incidence of childhood T1D in Western Australia, following a peak in 2003 ...

        Research

        Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: a pooled analysis from the childhood Leukemia International Consortium

        Our findings suggest that high coffee intake during pregnancy may increase risk of childhood acute lymphoblastic leukemia ...

        Research

        Influenza vaccination in pregnancy among a group of remote dwelling Aboriginal and Torres Strait Islander mothers in the Northern Territory

        We examined uptake of inactivated influenza vaccination in pregnancy and report adverse birth outcomes amongst a predominantly unvaccinated group ...

        Research

        Lipidomics reveals associations of phospholipids with obesity and insulin resistance in young adults

        Lipidomic biomarkers associated with obesity and IR using plasma samples from a population-based cohort of young adults ...

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