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        Airway narrowing assessed by anatomical optical coherence tomography in vitro: dynamic airway wall morphology and function

        Previous histological and imaging studies have shown the presence of variability in the degree of bronchoconstriction of airways sampled at different locations. ...

        Research

        Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy

        Topical application of tumors with the TLR7 agonist imiquimod is an effective adjunct treatment for a range of primary dermatological cancers. ...

        Research

        Findings from the Kids in Communities Study (KiCS): A mixed methods study examining community-level influences on early childhood development

        There is increasing international interest in place-based approaches to improve early childhood development (ECD) outcomes. The available data and evidence are limited and precludes well informed policy and practice change. Developing the evidence-base for community-level effects on ECD is one way to facilitate more informed and targeted community action. ...

        Research

        Parainfluenza Virus Infection in an Australian Community-based Birth Cohort

        In a community-based birth cohort of 158 Australian infants followed to age 2 years, the incidence rate of human parainfluenza virus (HPIV) was 0.42 (95% CI = 0.33, 0.54) episodes per child-year with episodes occurring year-round, peaking in the spring season. ...

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        Healing Right Way: Study protocol for a stepped wedge cluster randomised controlled trial to enhance rehabilitation services and improve quality of life in Aboriginal Australians after brain injury

        Despite higher incidence of brain injury among Aboriginal compared with non-Aboriginal Australians, suboptimal engagement exists between rehabilitation services and Aboriginal brain injury survivors. Aboriginal patients often feel culturally insecure in hospital and navigation of services post discharge is complex. ...

        Research

        Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth

        Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. ...

        Research

        Gender Gaps in Cognitive and Non Cognitive Skills in Early Primary Grades: Evidence from Rural Indonesia

        This paper examines gender gaps in cognitive and non-cognitive skills among a sample of more than 10,000 children between the ages of 6 and 9 in rural Indonesia ...

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        A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010

        Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a... ...

        Research

        Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography

        Previous histological and imaging studies have shown the presence of variability in the degree of bronchoconstriction of airways sampled at different locations. ...

        Research

        Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

        Epigenetics links perinatal influences with later obesity. We identifed differentially methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity measures and examined whether these were associated with hsCRP, adipokines, and early life environmental factors. Genome-wide DNA methylation from 1192 Raine Study participants at 17 years, identified 29 dmCpGs associated with body mass index, 10 with waist circumference and 9 with subcutaneous fat thickness. ...

        Research

        Fetal alcohol spectrum disorder resources for health professionals: a scoping review protocol

        People with fetal alcohol spectrum disorder (FASD) encounter a range of health and allied health providers and require specialised support to ensure health services are provided safely and effectively. Not all health professionals possess the knowledge or expertise required for the identification, assessment, referral and management of FASD. ...

        Research

        Cyber-Friendly Schools

        This chapter describes a whole-school cyberbullying intervention developed and evaluated in Western Australia with secondary school students aged 13–18 years old ...

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