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        25-36 of 94 results for 'PROTECT trial'

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        Evaluation of a bacterial therapy for prevention of respiratory infection including influenza and otitis media

        Deborah Jean-Francois Lea-Ann Peter Ruth Strickland Lauzon-Joset Kirkham Richmond Thornton DH JFLJ LK PC RT PhD PhD MBBS MRCP(UK) FRACP PhD Program Head, Immunobiology and Immunotherapeutic Program Senior Research Officer Co-Head, Bacterial ...

        Research

        Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: a randomised controlled trial of PCV in Papua New Guinean infants

        Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting ...

        Research

        Does mum know best? Should we be vaccinating mothers to protect their babies from ear and lung disease?

        Elke Lea-Ann Ruth Peter Seppanen Kirkham Thornton Richmond ES LK RT PC BSc PhD PhD PhD MBBS MRCP(UK) FRACP Program Manager, Bacterial Respiratory Infectious Disease Group Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, ...

        Research

        Targeting the mucosal immune system in a mouse model to prevent pregnancy complications following maternal bacterial infection

        Susan Pat Deborah Prescott Holt Strickland SL PG DH MBBS BMedSci PhD FRACP PhD, DSc, FRCPath, FRCPI, FAA PhD Honorary Research Fellow Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic Program susan.prescott@ ...

        Research

        Pathogenesis of obstructive sleep apnoea

        Lea-Ann Peter Ruth Kirkham Richmond Thornton LK PC RT PhD MBBS MRCP(UK) FRACP PhD Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, Wesfarmers Centre of Vaccines & Infectious Diseases Head, Vaccine Trials Group Co-head, ...

        Research

        Links2HealthierBubs' cohort study: Protocol for a study on the safety, uptake and effectiveness of influenza and pertussis vaccines among pregnant Australian women

        Multi-jurisdictional cohort of mother-infant pairs to measure the uptake, safety and effectiveness of antenatal IIV and dTpa vaccines in three Australian jurisdictions ...

        Research

        Children with otitis media mount a pneumococcal serotype specific serum IgG and IgA response comparable to healthy controls after pneumococcal conjugate vaccination

        We investigated the suggestion that otitis-prone children have an impaired antibody response in the context of pneumococcal vaccination. ...

        Research

        Microbiological and immunological factors predicting surgical outcomes for chronic otitis media

        Lea-Ann Peter Ruth Kirkham Richmond Thornton LK PC RT PhD MBBS MRCP(UK) FRACP PhD Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, Wesfarmers Centre of Vaccines & Infectious Diseases Head, Vaccine Trials Group Co-head, ...

        Research

        Sleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies

        The underlying pathogenesis of pediatric obstructive sleep disordered breathing (SDB) and recurrent tonsillitis (RT) are poorly understood but need to be elucidated to develop less invasive treatment and prevention strategies. ...

        Research

        Understanding the aetiology and resolution of chronic otitis media from animal and human studies

        This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition ...

        Research

        Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease

        Chronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function ...

        Research

        No evidence for impaired humoral immunity to pneumococcal proteins in Australian Aboriginal children with otitis media

        Conserved vaccine candidate proteins from S.pneumoniae induce serum and salivary antibody responses in Aboriginal and non-Aboriginal children with history of OM ...

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