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        25-36 of 42 results for 'colonisation'

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        Improved diagnosis, treatment and prevention of recurrent tonsillitis

        Anthony Janessa Ruth Tim Kicic Pickering Thornton Barnett A Dr RT TB BSc (Hons) PhD BSc PhD PhD PhD Rothwell Family Fellow; Head, Airway Epithelial Research Senior Research Fellow (currently HOT NORTH Early Career Fellow) Co-head, Bacterial ...

        Research

        Performance and Practicality of a Rapid Molecular Test for the Diagnosis of Strep A Pharyngitis in a Remote Australian Setting

        Over 5 days, 120 schoolchildren from two schools in the remote Kimberley region of Australia were screened for Strep A pharyngitis. Molecular point-of-care testing identified Strep A pharyngitis in 13/18 (72.2%) symptomatic children. The portability and feasibility of molecular point-of-care testing was highly practical for remote settings. ...

        Research

        Pcv7-and pcv10-vaccinated otitis-prone children in new zealand have similar pneumococcal and haemophilus influenzae densities in their nasopharynx and middle ear

        PCV10 did not reduce NTHi density in the nasopharynx or middle ear, and was associated with increased pneumococcal nasopharyngeal density ...

        Research

        HipHop2SToP a community-led health promotion initiative empowering Aboriginal youth in the Kimberley region of Western Australia: a process evaluation

        For millennia, Aboriginal people's ways of knowing, doing and being were shared through art, song, and dance. Colonisation silenced these ways, affecting loss of self-determination for Aboriginal people. Over the past decade in Australia, hip-hop projects have become culturally appropriate approaches for health promotion.  ...

        Research

        Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporter

        Described antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of antibiotics and can be monitored by in vitro susceptibility testing and genetic methods. Here we describe a mechanism of sulfamethoxazole resistance that requires a host metabolite for activity. ...

        Research

        Roadmap to incorporating group A Streptococcus molecular point-of-care testing for remote Australia: a key activity to eliminate rheumatic heart disease

        Jonathan Asha Dylan Rosemary Janessa Carapetis AM Bowen Barth Wyber Pickering JR AC DB R Dr AM MBBS FRACP FAFPHM PhD FAHMS BA MBBS DCH FRACP PhD GAICD OAM B.Tech, MPH, PhD MBChB MPH FRACGP PhD BSc PhD Executive Director; Head, Strep A Translation; ...

        Research

        Immunogenicity of pneumococcal vaccine schedules in high-risk infants in Papua New Guinea

        Deborah Lea-Ann Peter Peter Ruth Lehmann Kirkham Jacoby Richmond Thornton D LK PJ PC RT AO, MBBS, MSc PhD BA (Hons) MSc MBBS MRCP(UK) FRACP PhD Honorary Emeritus Fellow Co-Head, Bacterial Respiratory Infectious Disease Group; Microbiology Lead, ...

        Research

        Standardization of Epidemiological Surveillance of Group A Streptococcal Pharyngitis

        Pharyngitis, more commonly known as sore throat, is caused by viral and/or bacterial infections. Group A Streptococcus (Strep A) is the most common bacterial cause of pharyngitis. Strep A pharyngitis is an acute, self-limiting disease but if undertreated can lead to suppurative complications, nonsuppurative poststreptococcal immune-mediated diseases, and toxigenic presentations. ...

        Research

        Science of the swab: optimising Strep A typing from clinical samples

        Asha Dylan Janessa Tim Bowen Barth Pickering Barnett AC DB Dr TB BA MBBS DCH FRACP PhD GAICD OAM B.Tech, MPH, PhD BSc PhD PhD Head, Healthy Skin and ARF Prevention Postdoctoral Research Fellow / Epidemiologist Senior Research Fellow (currently HOT ...

        Research

        Standardization of Epidemiological Surveillance of Group A Streptococcal Impetigo

        Impetigo is a highly contagious bacterial infection of the superficial layer of skin. Impetigo is caused by group A Streptococcus (Strep A) and Staphylococcus aureus, alone or in combination, with the former predominating in many tropical climates. Strep A impetigo occurs mainly in early childhood, and the burden varies worldwide. It is an acute, self-limited disease, but many children experience frequent recurrences that make it a chronic illness in some endemic settings. ...

        Research

        Standardization of Epidemiological Surveillance of Invasive Group A Streptococcal Infections

        Invasive group A streptococcal (Strep A) infections occur when Streptococcus pyogenes, also known as beta-hemolytic group A Streptococcus, invades a normally sterile site in the body. This article provides guidelines for establishing surveillance for invasive Strep A infections. The primary objective of invasive Strep A surveillance is to monitor trends in rates of infection and determine the demographic and clinical characteristics of patients with laboratory-confirmed invasive Strep A infection, the age- and sex-specific incidence in the population of a defined geographic area, trends in risk factors, and the mortality rates and rates of nonfatal sequelae caused by invasive Strep A infections. ...

        Research

        A pilot study to develop assessment tools for Group A Streptococcus surveillance studies

        Group A Streptococcus (GAS) causes pharyngitis (sore throat) and impetigo (skin sores) GAS pharyngitis triggers rheumatic fever (RF) with epidemiological evidence supporting that GAS impetigo may also trigger RF in Australian Aboriginal children. Understanding the concurrent burden of these superficial GAS infections is critical to RF prevention. This pilot study aimed to trial tools for concurrent surveillance of sore throats and skins sore for contemporary studies of RF pathogenesis including development of a sore throat checklist for Aboriginal families and pharynx photography. ...

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