Research focused on Down syndrome has increased in the last several years to advance understanding of the consequences of trisomy 21 (T21) on molecular and cellular processes and, ultimately, on individuals with Down syndrome. The Trisomy 21 Research Society (T21RS) is the premier scientific organization for researchers and clinicians studying Down syndrome. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutation to a leukemia driven by additional driver mutations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

Lung function measures in a health, unsedated 1- and 2-year-old children in a South African birth cohort study ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• November 2016

In this article, the Group Chairs of the Paediatric Assembly of the European Respiratory Society (ERS) highlight some of the most interesting abstracts presented at the 2016 ERS International Congress, which was held in London. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

Haematological malignancies, although a broad range of specific disease types, continue to show considerable overlap in classification, and patients are... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

This paper is an introduction to a series of articles about improved measurement of lung function in patients with chronic lung disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

Towards the goal of malaria elimination on Hispaniola, the National Malaria Control Program of Haiti and its international partner organisations are conducting a campaign of interventions targeted to high-risk communities prioritised through evidence-based planning. Here we present a key piece of this planning: an up-to-date, fine-scale endemicity map and seasonality profile for Haiti informed by monthly case counts. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

This essay examines wages and the gender wage gap between 1993 and 2008 in Vietnam ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• September 2018

The link between respiratory and vascular health is well documented in adult populations. Impaired lung function is consistently associated with thicker arteries and higher incidence of cardiovascular disease. However, there are limited data on this relationship in young children and the studies that exist have focussed on populations at high risk of cardiorespiratory morbidity. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Sébastien Laurence Rishi Sury Malinge Cheung Kotecha SM LC RS PhD BPharm (Hons) MBA PhD MB ChB (Hons) MRCPCH FRACP PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior Research ...

• 1. Telethon Kids Institute
• Projects

We aimed to evaluate the effect of undernutrition on sputum culture conversion and treatment outcomes among people with multidrug-resistant tuberculosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sexdifferential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021