This chapter considers the role of different forms of psychosocial adversity as risk factors for compromised language and literacy development in childhood and adolescence. Language skills play a central role in the development of prosocial interpersonal skills as well as promoting academic success through the transition to literacy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

Many humans suffer from allergic disease, which often develops in early life years, can be severe, and impose a significant burden over the course of their lives. Why some people develop disease and others do not is still not well understood. We are ...

• 1. Telethon Kids Institute
• Our research
• Early Environment
• Immunobiology & Immunotherapeutic Program
• Pregnancy and Early Life Immunology

Our results suggest that reciprocal influences between alpha1-adrenoceptors and inflammatory cytokines may play a role in normal inflammatory responses ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Natural killer (NK) cells play a significant and vital role in the first line of defense against infection through their ability to target cells without prior sensitization. They also contribute significantly to the activation and recruitment of both innate and adaptive immune cells through the production of a range of cytokines and chemokines. In the context of cytomegalovirus (CMV) infection, NK cells and CMV have co-evolved side by side to employ several mechanisms to evade one another. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

Combined vaccines have an increasingly important role to play in delivering these antigens acceptably. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2007
• September 2007

Naturalistic developmental behavioural interventions are promising approaches for young children with, or suspected of having, autism spectrum disorder. Joint attention, symbolic play, engagement and regulation intervention (JASPER) is a well-researched naturalistic developmental behavioural intervention but, to date, no reviews have specifically evaluated its effects. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Esophageal squamous cell carcinoma (ESCC) is a prevalent malignant tumor of the digestive tract with a low 5-year survival rate due to the lack of effective treatment methods. Although therapeutic monoclonal antibodies (mAbs) now play an important role in cancer therapy, effective targeted mAbs are still lacking for ESCC.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Beyond the use of policy and system-focused approaches, it has been established globally that patients can play a role in enhancing the health care landscape. However, efforts to meaningfully translate patient engagement strategies that promote participation by hospitalized patients in relevant infection prevention and antimicrobial stewardship activities have not yet been realized. This study mapped the key factors acting as barriers and facilitators of patient engagement using a theoretical framework to identify potential new approaches to promote engagement. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

Hayley Christian HC BSc (1st Class Hons), PhD W.Aust. Program Head, Healthy Behaviours and Environments; National Heart Foundation Future Leader Fellow 08 6319 1040 hayley.christian@telethonkids.org.au Program Head, Healthy Behaviours and ...

• 1. Telethon Kids Institute
• Projects
• Past projects

This study investigated where preschool children were more or less active in outdoor play areas in Early Childhood Education and Care (ECEC) centers using a novel method of combined device-measured physical activity, spatial data and on-site audit data. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

It has been proposed that interpersonal problems play a role in the maintenance of disordered eating because of an adverse effect on self-esteem, which in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• September 2011

Highly pathogenic avian influenza A virus (H5N1) is a leading candidate for the next influenza pandemic, and infants and children may play an important role... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2008
• November 2008