In most individuals, language production and visuospatial skills are subserved predominantly by the left and right hemispheres, respectively. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• November 2009

Developmental language disorder is a heterogeneous diagnostic category. Little research has compared the long-term outcomes of children with different... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• July 2009

The application of the systematic review improved inter-observer agreement but did not affect reported multiple breath washout outcomes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

De novo S. aureus acquisition at age 3 is associated with later bronchiectasis and FEF25-75 in children with CF ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

Consensus recommendations are outlined to direct preschool device design, test performance, and data analysis for the MBW technique ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

Group A Streptococcus (Strep A) is responsible for a significant global health and economic burden. The recent prioritization of Strep A vaccine development by the World Health Organization has prompted global research activities and collaborations. To progress this prioritization, establishment of robust surveillance for Strep A to generate updated regional disease burden estimates and to establish platforms for future impact evaluation is essential. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Preterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to meet targets set for ending the epidemic by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Sustainable Development Goals (SDGs). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Measurement of lung volumes across the life course is critical to the diagnosis and management of lung disease. The aim of the study was to use the Global Lung Function Initiative methodology to develop all-age multi-ethnic reference equations for lung volume indices determined using body plethysmography and gas dilution techniques. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

T cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy with inferior outcome compared with that of B cell ALL. Here, we show that Runt-related transcription factor 2 (RUNX2) was upregulated in high-risk T-ALL with KMT2A rearrangements (KMT2A-R) or an immature immunophenotype. In KMT2A-R cells, we identified RUNX2 as a direct target of the KMT2A chimeras, where it reciprocally bound the KMT2A promoter, establishing a regulatory feed-forward mechanism. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

Children born preterm have impaired lung function and altered lung structure. However, there are conflicting reports on how preterm birth impacts aerobic exercise capacity in childhood. We aimed to investigate how neonatal history and a diagnosis of bronchopulmonary dysplasia (BPD) impact the relationship between function and structure of the lung, and aerobic capacity in school-aged children born very preterm. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• June 2017