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        Multidrug-resistant tuberculosis in Western Australia, 1998-2012

        Our objective was to describe the epidemiology, clinical features, health care resource use, treatment and outcomes of multidrug-resistant tuberculosis... ...

        Research

        An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution

        Typhoid fever is a major global health problem, the control of which is hindered by lack of a suitable animal model in which to study Salmonella Typhi... ...

        Research

        What do infectious diseases physicians do? A 2-week snapshot of inpatient consultative activities across Australia, New Zealand and Singapore

        We performed a 2-week prospective survey of formal ID physician activities related to direct inpatient care, encompassing 53 hospitals throughout Australia,... ...

        Research

        Molecular tools for differentiation of non-typeable Haemophilus influenzae from Haemophilus haemolyticus

        The molecular approaches that have been developed for differentiation of NTHi from H. haemolyticus, with the advantages and disadvantages of each target ...

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        A randomized phase I study of the safety and immunogenicity

        In this study of healthy adults aged 50-85 and 18-24 years, SA3Ag elicited a rapid and robust immune response and was well tolerated, with no notable safety... ...

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        Antibody persistence in Australian adolescents following meningococcal C conjugate vaccination

        In Australia, following the introduction of serogroup C meningococcal (MenC) conjugate vaccine for toddlers and catch-up immunization through adolescence,... ...

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        Hierarchy and molecular properties of house dust mite allergens

        The allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity. ...

        Research

        CD46 measles virus receptor polymorphisms influence receptor protein expression

        Despite the availability of measles vaccines, infants continue to die from measles. Measles vaccine responses vary between individuals, and poor... ...

        Research

        Toll-like receptor 7 and 8 polymorphisms: Associations with functional effects and cellular and antibody responses to measles virus and vaccine

        The functionality and effects of TLR7 and TLR8 polymorphisms on cellular and antibody responses was investigated after the first measles vaccine dose. ...

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        Genetic and functional evidence implicating DLL1 as the gene that influences susceptibility

        Visceral leishmaniasis (VL) is caused by Leishmania donovani and Leishmania infantum chagasi. Genome-wide linkage studies from Sudan and Brazil identified... ...

        Research

        Increased allergic immune response to Sarcoptes scabiei antigens in crusted versus ordinary scabies

        Pat Belinda Holt Hales PG BJ PhD, DSc, FRCPath, FRCPI, FAA BSc (Hons) PhD Emeritus Honorary Researcher Senior Manager, Research Platforms Patrick.Holt@telethonkids.org.au belinda.hales@telethonkids.org.au Emeritus Honorary Researcher Senior Manager ...

        Research

        Do early-life viral infections cause asthma?

        Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known ...

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