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        Effectiveness of rotavirus vaccines in an Australian population: A case-control study

        RV1 and RV5 were both effective in preventing laboratory confirmed and notified rotavirus infections among children aged <5 years ...

        Research

        Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiency

        Malt1 deficient mice develop an osteoporotic phenotype with increased osteoclastogenesis in vivo, but suggest that this is caused by inflammation ...

        Research

        Maternal Smoking During Pregnancy Induces Epigenetic Changes Into Adolescence, Independent of Postnatal Smoke Exposure and Is Associated With Cardiometabolic Risk

        This study demonstrates a critical timing of cigarette smoke exposure over the life course for establishing persistent changes in DNA methylation into adolescence ...

        Research

        In Epigenomic Studies, Including Cell-Type Adjustments in Regression Models Can Introduce Multicollinearity, Resulting in Apparent Reversal of Direction of Association

        Where cell types are highly correlated with other covariates in regression models, the statistical assumption of no multicollinearity may be violated ...

        Research

        Glutathione S-Transferase Genotype Protects against in Utero Tobacco-linked Lung Function Deficits

        Certain glutathione S-transferase genotypes may have protective effects against the long-term deficits in lung function associated with in utero tobacco exposure ...

        Research

        Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children

        Bacterial airway microbiome is highly variable in early life and its role in wheeze remains less clear than viral influences ...

        Research

        Association between pregnant women's experience of stress and partners’ fly-in-fly-out work

        There is some evidence that the pregnant partners of fly-in-fly-out workers perceive their lives to be more stressful ...

        Research

        Evolving Trends of Gastrostomy Insertion Within a Pediatric Population

        New gastrostomy insertion among children who require long-term enteral feeding support increased over the study period ...

        Research

        Moraxella catarrhalis Restriction-Modification Systems Are Associated with Phylogenetic Lineage and Disease

        We observed an association between Type III DNA methyltransferase presence and Otitis Media-associated middle ear isolates ...

        Research

        Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations

        Our findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations ...

        Research

        Increased prevalence of expiratory flow limitation during exercise in children with bronchopulmonary dysplasia

        Expiratory flow limitation is more prevalent in children born preterm with bronchopulmonary dysplasia and is associated with airway obstruction ...

        Research

        Real-world outcomes of insulin pump compared to injection therapy in a population-based sample of children with type 1 diabetes

        Patients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort ...

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