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        Bowel patterns, gastrointestinal symptoms, and emotional well-being in adolescents: A cohort study

        In adolescents, bowel patterns and gastrointestinal symptoms are diverse and show sex differences ...

        Research

        Genetic Manipulation of Group A Streptococcus-Gene Deletion by Allelic Replacement

        An optimized, rapid method for creating markerless isogenic mutations that combines Gibson assembly cloning with a new temperature-sensitive plasmid, pLZts ...

        Research

        Towards the development of an integrative, evidence-based suite of indicators for the prediction of outcome following mild traumatic brain injury

        Performance on neuropsychological measures may be useful for predicting persisting post-concussion symptoms ...

        Research

        Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma model

        We established a pipeline to assess the effects of epigenetic modifiers on CD8+ T cell proliferation, differentiation, and efficacy in a preclinical melanoma model ...

        Research

        Early life determinants of health: Invest early to break the cycle of long-term disadvantage in neurodevelopmental disorders

        This chapter discusses the importance of investment in early life determinants of health to break the cycle of long-term disadvantage. This chapter addresses these issues while focussing on neurodevelopmental disorders and their related mental health concerns as the targets at the centre of a biopsychosocial transformation of the health system. ...

        Research

        CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: Study protocol for a randomised controlled trial

        This study will assess the effect of adjunctive clindamycin on patient-centred outcomes in severe, toxin-mediated S. aureus infections ...

        Research

        Personalized transcriptomics reveals heterogeneous immunophenotypes in children with viral bronchiolitis

        Dysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants ...

        Research

        Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes

        These findings suggest the utility of specific FOT outcomes is dependent on the respiratory disease being assessed ...

        Research

        Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

        The WHF echocardiographic criteria enable reproducible categorisation of echocardiograms as definite RHD versus no or borderline RHD ...

        Research

        Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial

        Determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases the risk of perioperative respiratory adverse events ...

        Research

        Factors influencing participation in home, school, and community settings by children and adolescents with neuromuscular disorders: A qualitative descriptive study

        This study explored how children and adolescents with a neuromuscular disorder (NMD) and their parents experienced barriers and enablers to the child's participation. ...

        Research

        Real world impact of 13vPCV in preventing invasive pneumococcal pneumonia in Australian children: A national study

        We aimed to assess the direct protective effect of 13 valent pneumococcal conjugate vaccine (13vPCV) against invasive pneumococcal pneumonia (IPP; including pneumonia and empyema) in children using a nation-wide case-control study across 11 paediatric tertiary hospitals in Australia. ...

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