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        Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy

        Our data indicate epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex, and likely reflects pathways modified by gene-environment interactions in food allergy ...

        Research

        Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle?

        This study investigates the variation of human milk metabolites in human milk between five different countries ...

        Research

        Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions

        This is the first report examining the role of different rhinovirus species in ARIs in children admitted to a tertiary PICU ...

        Research

        The Canmore Declaration: Statement of Principles for Planetary Health

        We provide the Canmore Declaration, a Statement of Principles for Planetary Health ...

        Research

        Does otitis media in early childhood affect later behavioural development? Results from the Western Australian Pregnancy Cohort (Raine) Study

        The relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders. ...

        Research

        Teleaudiology services for rehabilitation with hearing aids in adults: A systematic review

        This review provides up-to-date evidence for teleaudiology hearing aid services in new and experienced hearing aid users in different practice settings ...

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        Cellular and molecular mechanisms of vitamin D in food allergy

        Epidemiological evidence from the past decade suggests a role of vitamin D in food allergy pathogenesis ...

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        Large-Scale Structural Variation Detection in Subterranean Clover Subtypes Using Optical Mapping

        The accuracy of structural variations detection by Bionano optical mapping is highly dependent on the quality of reference genomes and the density of selected nickases ...

        Research

        Epigenetic dysregulation of host gene expression in Toxoplasma infection with specific reference to dopamine and amyloid pathways

        Our results provide a possible functional link between Toxoplasma gondii infection and congenital/early life and adult neurological clinical signs ...

        Research

        β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating Peptides

        The β-lactamase assays provide compatible tools for functional characterization of CPP activity and the delivery of biological cargos into cells ...

        Research

        Vagus nerve stimulation for the treatment of refractory epilepsy in the CDKL5 Deficiency Disorder

        Our study suggests that vagus nerve stimulation is a generally safe and effective adjunct treatment for CDKL5-associated epilepsy ...

        Research

        What effect does regular exercise have on oxidative stress in people with Down syndrome? A systematic review with meta-analyses

        There remains uncertainty about the effect of exercise on oxidative stress in people with Down syndrome ...

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