Patients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

Research and research funding must be independent of the tobacco industry, which continues to cause so much suffering ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

The risk of intellectual disability was increased in children born after assisted reproductive technology in Western Australia from 1994 to 2002 ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

This study investigated the use of a carbohydrate intake algorithm based on continuous glucose monitoring trends during physical activity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

Here, we review the basic concepts in bioinformatics and genomic data analysis and illustrate the application of these tools to further our understanding of lung diseases ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

This paper is the first to explore whether differences in time use by children of Asian-born parents may help to explain the observed differentials in school achievements ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

Early identification of oropharyngeal dysphagia and the management of seizures may help prevent serious respiratory illness ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

The RHD Endgame Strategy: the blueprint to eliminate rheumatic heart disease in Australia by 2031 (the Endgame Strategy) is the blueprint to eliminate rheumatic heart disease (RHD) in Australia by 2031. Aboriginal and Torres Strait Islander people live with one of the highest per capita burdens of RHD in the world. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

Maternal stressful life events during pregnancy have been associated with immune dysregulation and increased risk for asthma and atopy in offspring. Few studies have investigated whether prenatal stress is associated with increased overall or specific infectious diseases in childhood, nor explored sex differences. We sought to examine the relationship between the nature and timing of maternal stress in pregnancy and hospitalisation with infection in offspring. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Benzathine penicillin G has been used as monthly deep intramuscular (IM) injections since the 1950s for secondary prevention of acute rheumatic fever and rheumatic heart disease (RHD). Injection frequency and pain are major programmatic barriers for adherence, prompting calls for development of better long-acting penicillin preparations to prevent RHD. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Cancer cells display DNA hypermethylation at specific CpG islands in comparison to their normal healthy counterparts, but the mechanism that drives this so-called CpG island methylator phenotype (CIMP) remains poorly understood. Here, we show that CpG island methylation in human T-cell acute lymphoblastic leukemia (T-ALL) mainly occurs at promoters of Polycomb Repressor Complex 2 (PRC2) target genes that are not expressed in normal or malignant T-cells and which display a reciprocal association with H3K27me3 binding. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020