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        Aboriginal parent support: A partnership approach

        Our aim was to identify program elements, exploring participants’ perceptions of the program's suitability, feasibility, acceptability and effectiveness. ...

        Research

        Latent profiles of early developmental vulnerabilities in a New South Wales child population at age 5 years

        Patterns of early childhood developmental vulnerabilities may provide useful indicators for particular mental disorder outcomes in later life ...

        Research

        Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults

        Type 2 inflammation is present in patients during virus-induced asthma exacerbations, to the same degree as non-viral exacerbations ...

        Research

        Assessment of early bronchiectasis in young children with cystic fibrosis is dependent on lung volume

        The aim of this study was to determine whether assessment of early CT scan-detected bronchiectasis in young children with cystic fibrosis (CF) depends on... ...

        Research

        Variants near CCNL1/LEKR1 and in ADCY5 and Fetal Growth Characteristics in Different Trimesters

        A recent genome-wide association study identified variants near CCNL1/LEKR1 (rs900400) and in ADCY5 (rs9883204) to be associated with birth weight. ...

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        10-Valent pneumococcal non-typeable H. influenzae protein D conjugate vaccine versus 13-valent pneumococcal conjugate vaccine (PCV13) as a booster dose

        18 months of age infants receiving 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine will have higher antibody levels ...

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        Children's neighbourhood physical environment and early development: an individual child level linked data study

        The neighbourhood physical environment has a weak but significant association with early childhood development ...

        Research

        Prevalence and risk factors for parent-reported recurrent otitis media during early childhood

        The prevalence of parent-reported rOM was 26.8% (611/2280) and 5.5% (125/2280) for severe rOM in the Study. ...

        Research

        Correlating Quantitative and Genomic SARS-CoV-2 Wastewater Data with Clinical Metrics in Metropolitan Perth, Western Australia

        Wastewater-based epidemiology (WBE) has emerged as a key method for the continuous monitoring of COVID-19 prevalence including circulating SARS-CoV-2 lineages. WBE addresses the limitations of traditional clinical COVID-19 surveillance such as clinical test availability, fluctuating testing rates, and increased reliance on rapid antigen tests.  ...

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        Mutational rescue of the activity of high-fidelity Cas9 enzymes

        Programmable DNA endonucleases derived from bacterial genetic defense systems, exemplified by CRISPR-Cas9, have made it significantly easier to perform genomic modifications in living cells. However, unprogrammed, off-target modifications can have serious consequences, as they often disrupt the function or regulation of non-targeted genes and compromise the safety of therapeutic gene editing applications.  ...

        Research

        Prognostic significance of molecular subgroups in survival outcome for children with medulloblastoma in Malaysia

        Advancements in genomic profiling led to the discovery of four major molecular subgroups in medulloblastoma (MB), which have now been incorporated into the World Health Organization classification of central nervous system tumors. The current study aimed to determine the prognostic significance of the MB molecular subgroups among children in Malaysia.  ...

        Research

        Still keen and committed: piloting an instrument for identifying positive veteran teachers

        Initial findings suggest the potential of the instrument in helping identifying positive veteran teachers within systems, as well as the voracity of the research approach ...

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