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        Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data

        Here we compare the performance of several LMM approaches (and software implementations, including EMMAX, GenABEL, FaST-LMM, Mendel, GEMMA and MMM) via their... ...

        Research

        Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus

        We found a novel association between intraocular pressure and a common variant at 7p21 near to GLCCI1 and ICA1. ...

        Research

        Pharmacokinetics of intramuscular versus subcutaneous administration of Benzathine Penicillin G

        Jonathan Rosemary Carapetis AM Wyber JR R AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Senior Research Fellow 08 6319 1000 contact@telethonkids.org.au Institute Director; Head ...

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        Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis

        Congenital Toxoplasma gondii infection can result in intracranial calcification, hydrocephalus and retinochoroiditis. Acquired infection is commonly associated ...

        Research

        Immunogenetics of Parasitic and Bacterial Disease

        Here we focus on more recent well-powered genome-wide association studies, including malaria, leprosy, tuberculosis, and visceral leishmaniasis ...

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        Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

        Identified an association between polymorphisms in a long intergenic non-coding RNA (lincRNA) gene (AC011288.2) and pneumococcal bacteremia ...

        Research

        The correlation between reading and mathematics ability at age twelve has a substantial genetic component

        Dissecting how genetic and environmental influences impact on learning is helpful for maximizing numeracy and literacy. ...

        Research

        Hospital admissions for skin infections among Western Australian children and adolescents from 1996 to 2012

        The objective of this study was to describe the occurrence of skin infection associated hospitalizations in children born in Western Australia (WA). ...

        Research

        The Impact of a Multifaceted Tertiary Pediatric Hospital's Antimicrobial Stewardship Service

        Antimicrobials are the most commonly prescribed drug class in children. Overuse through inappropriate prescribing is a key driver of antimicrobial resistance and is recognized as one of the top 10 threats to global health by the World Health Organization. ...

        Research

        Performance and Practicality of a Rapid Molecular Test for the Diagnosis of Strep A Pharyngitis in a Remote Australian Setting

        Over 5 days, 120 schoolchildren from two schools in the remote Kimberley region of Australia were screened for Strep A pharyngitis. Molecular point-of-care testing identified Strep A pharyngitis in 13/18 (72.2%) symptomatic children. The portability and feasibility of molecular point-of-care testing was highly practical for remote settings. ...

        Research

        Reference exome data for Australian Aboriginal populations to support health-based research

        Our data set provides a useful reference point for genomic studies on Aboriginal Australians ...

        Research

        Children with secondary care episodes for otitis media have poor literacy and numeracy outcomes: A data linkage study

        We examined the association between otitis media and educational attainment in a retrospective population cohort of Western Australian children who participated in the Grade 3 National Assessment Program—Literacy and Numeracy in 2012. ...

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